正常和去神经大鼠骨骼肌肌浆网的特征
Characteristics of sarcoplasmic reticulum from normal and denervated rat skeletal muscle.
作者信息
Palexas G N, Savage N, Isaacs H
出版信息
Biochem J. 1981 Oct 15;200(1):11-5. doi: 10.1042/bj2000011.
Abstract
Denervation of rat skeletal muscle produces after 14 days a decrease in Ca2+ uptake of a heterogeneous population of sarcoplasmic-reticulum vesicles, when measured in the presence of oxalate. The Mg2+-dependent ATPase (Ca2+-independent) activity increased after the same period and the Ca2+ + Mg2+-dependent ATPase activity decreased. Concomitant with these changes, there was an increase in vesicle size and calcium content. The observations are discussed in terms of changes in altered membrane structure, manifested in the shift of the equilibrium of the ATPase from an enzyme involved in calcium transport to a phosphoenzyme giving rise to an increase in the Mg2+-dependent ATPase activity.
摘要
对大鼠骨骼肌进行去神经支配处理后，在第14天，当在草酸盐存在的情况下进行测量时，肌浆网囊泡异质群体的钙离子摄取量会减少。同期，镁离子依赖性ATP酶（与钙离子无关）活性增加，而钙离子与镁离子依赖性ATP酶活性降低。伴随着这些变化，囊泡大小和钙含量增加。这些观察结果从膜结构改变的角度进行了讨论，这种改变表现为ATP酶平衡从参与钙转运的酶转变为导致镁离子依赖性ATP酶活性增加的磷酸酶。
相似文献
1
Characteristics of sarcoplasmic reticulum from normal and denervated rat skeletal muscle.正常和去神经大鼠骨骼肌肌浆网的特征
Biochem J. 1981 Oct 15;200(1):11-5. doi: 10.1042/bj2000011.
2
The effect of hypothyroidism on sarcoplasmic reticulum in fast-twitch muscle of the rat.甲状腺功能减退对大鼠快肌肌浆网的影响。
Biochim Biophys Acta. 1985 Feb 21;844(2):129-41. doi: 10.1016/0167-4889(85)90083-7.
3
Calcium binding protein changes of sarcoplasmic reticulum from rat denervated skeletal muscle.大鼠失神经支配骨骼肌肌浆网钙结合蛋白的变化
Biosci Rep. 1988 Aug;8(4):369-78. doi: 10.1007/BF01115228.
4
Alteration of sarcoplasmic reticulum after denervation of chicken pectoralis muscle.鸡胸肌去神经支配后肌浆网的改变。
Biochem J. 1983 Feb 15;210(2):339-44. doi: 10.1042/bj2100339.
5
[Calcium transport and ATPase activity of sarcoplasmic reticulum in normal and denervated rabbit muscles].[正常及去神经支配兔肌肉中肌浆网的钙转运及ATP酶活性]
Biull Eksp Biol Med. 1976 May;81(5):536-9.
6
[Effect of cAMP-dependent phosphorylation on the activity of Mg2+,Ca2+-ATP-ase and Ca2+ transport in the sarcoplasmic reticulum of the white skeletal muscles of the rabbit].
Ukr Biokhim Zh (1978). 1984 Mar-Apr;56(2):141-6.
7
Effects of adrenalectomy and in vivo administration of dexamethasone on ATP-dependent calcium accumulation by sarcoplasmic reticulum from rat heart.肾上腺切除术及地塞米松体内给药对大鼠心脏肌浆网ATP依赖性钙蓄积的影响。
J Mol Cell Cardiol. 1983 Jan;15(1):7-15. doi: 10.1016/0022-2828(83)90303-6.
8
The effect of Mg2+ on cardiac muscle function: Is CaATP the substrate for priming myofibril cross-bridge formation and Ca2+ reuptake by the sarcoplasmic reticulum?镁离子对心肌功能的影响：钙三磷酸腺苷是否是引发肌原纤维横桥形成和肌浆网摄取钙离子的底物？
Biochem J. 2001 Mar 15;354(Pt 3):539-51. doi: 10.1042/0264-6021:3540539.
9
The effect of pH on the transient-state kinetics of Ca2+-Mg2+-ATPase of cardiac sarcoplasmic reticulum. A comparison with skeletal sarcoplasmic reticulum.pH对心肌肌浆网Ca2+-Mg2+-ATP酶瞬态动力学的影响。与骨骼肌肌浆网的比较。
Circ Res. 1982 Feb;50(2):310-7. doi: 10.1161/01.res.50.2.310.
10
Adaptive expression pattern of different proteins involved in cellular calcium homeostasis in denervated rat vas deferens.去神经大鼠输精管中参与细胞钙稳态的不同蛋白质的适应性表达模式
Eur J Pharmacol. 2005 Nov 21;525(1-3):54-9. doi: 10.1016/j.ejphar.2005.10.006. Epub 2005 Nov 14.
引用本文的文献
1
Increase in phospholamban content in mouse skeletal muscle after denervation.去神经支配后小鼠骨骼肌中受磷蛋白含量增加。
J Muscle Res Cell Motil. 2018 Dec;39(5-6):163-173. doi: 10.1007/s10974-019-09504-2. Epub 2019 Feb 26.
2
The denervated muscle: facts and hypotheses. A historical review.失神经肌肉：事实与假说。历史回顾。
Eur J Appl Physiol. 2006 Sep;98(1):1-21. doi: 10.1007/s00421-006-0256-z. Epub 2006 Aug 3.
3
Calcium current inactivation in denervated rat skeletal muscle fibres.去神经大鼠骨骼肌纤维中的钙电流失活
J Physiol. 1993 Jan;460:173-83. doi: 10.1113/jphysiol.1993.sp019465.
4
Alteration of sarcoplasmic reticulum after denervation of chicken pectoralis muscle.鸡胸肌去神经支配后肌浆网的改变。
Biochem J. 1983 Feb 15;210(2):339-44. doi: 10.1042/bj2100339.
5
Sarcoplasmic-reticulum biogenesis in contraction-inhibited skeletal-muscle cultures.收缩抑制的骨骼肌培养物中的肌浆网生物发生
Biochem J. 1992 Mar 1;282 ( Pt 2)(Pt 2):399-407. doi: 10.1042/bj2820399.
本文引用的文献
1
SARCOPLASMIC RETICULUM. I. THE UPTAKE OF CA++ BY SARCOPLASMIC RETICULUM FRAGMENTS.肌浆网。一、肌浆网片段对钙离子的摄取。
J Biol Chem. 1964 Feb;239:648-58.
2
A microcolorimetric method for the determination of inorganic phosphorus.一种测定无机磷的微量比色法。
J Biol Chem. 1953 Jun;202(2):675-85.
3
Highly purified sarcoplasmic reticulum vesicles are devoid of Ca2+-independent ('basal') ATPase activity.高度纯化的肌浆网囊泡缺乏不依赖钙离子的（“基础”）ATP酶活性。
Biochim Biophys Acta. 1980 Jul;599(2):552-68. doi: 10.1016/0005-2736(80)90199-6.
4
Cleavage of structural proteins during the assembly of the head of bacteriophage T4.在噬菌体T4头部组装过程中结构蛋白的切割
Nature. 1970 Aug 15;227(5259):680-5. doi: 10.1038/227680a0.
5
Fatty acid unsaturation and cholesterol content in normal and denervated muscle.正常和去神经肌肉中的脂肪酸不饱和度和胆固醇含量
Experientia. 1969 Dec 15;25(12):1242-3. doi: 10.1007/BF01897471.
6
Normal and denervated muscle. A morphometric study of fine structure.正常与失神经肌肉。精细结构的形态计量学研究。
Neurology. 1973 Jul;23(7):714-24. doi: 10.1212/wnl.23.7.714.
7
The effect of denervation on incorporation of 32P and (3H)glycerol by the muscle membrane.去神经对肌膜摄取32P和（3H）甘油的影响。
J Neurochem. 1970 May;17(5):613-20. doi: 10.1111/j.1471-4159.1970.tb00541.x.
8
Effect of denervation on fragmented sarcoplasmic reticulum of white and red muscle.
Exp Neurol. 1970 Oct;29(1):52-64. doi: 10.1016/0014-4886(70)90036-1.
9
Duchenne dystrophy: electron microscopic findings pointing to a basic or early abnormality in the plasma membrane of the muscle fiber.杜兴氏肌营养不良症：电子显微镜检查结果表明肌纤维质膜存在基本或早期异常。
Neurology. 1975 Dec;25(12):1111-20. doi: 10.1212/wnl.25.12.1111.
10
The effects of denervation on protein turnover of rat skeletal muscle.去神经支配对大鼠骨骼肌蛋白质周转的影响。
Biochem J. 1976 Apr 15;156(1):71-80. doi: 10.1042/bj1560071.
Zotero 插件