Results of donor artificial insemination (AID) in 415 couples.

During a 4.5-year period 415 spouses of infertile males were treated by artificial insemination with donor semen, resulting in 210 pregnancies (51%). An average of 7.1 insemination cycles and 11.5 inseminations was required to achieve a pregnancy. Thirty-six percent of the pregnancies occurred in the first cycle of treatment, 71.5% after three cycles of treatment, and 91.5% in six cycles. The abortion rate was 15%, comparable to that in the fertile population. The sex ratio of deliveries at time of reporting was 60 males to 62 females. For selected couples suffering from male sterility, artificial insemination with donor semen provides a reliable and therapeutically effective alternative to adoption.