Diebold J, Capron F, Temmim L
Ann Anat Pathol (Paris). 1977;22(3):221-32.
Histological examination of the various specimens taken during an exploratory laparotomy for Hodgkin's disease revealed the presence of epithelioid cells in 56 cases out of a total of 235 patients (i.e. 23.8 p. 100). These cells were disseminated throughout the lymphoid tissue or grouped in clumps, in plaques or, more rarely, as true follicles. They were found either in contact with Hodgkin's lesions or at a distance in organs free of disease. They were found in Lukes-Rye histological types 1, 2 and, above all, 3. Their significance remains unknown. The most likely hypotheses would appear to be those of a response to the accumulation of substances to be eliminated (tumour antigens?) or those of a disorder in cellular immunity.
在对霍奇金病进行剖腹探查时采集的各种标本的组织学检查显示，在总共235例患者中，有56例（即23.8%）存在上皮样细胞。这些细胞散布于整个淋巴组织中，或聚集成团、斑块状，或更罕见地形成真正的滤泡。它们既见于与霍奇金病变接触处，也见于无病变器官中的远处。在卢克斯-赖伊组织学类型1、2中发现了它们，尤其是在类型3中。它们的意义尚不清楚。最有可能的假说是对有待清除物质（肿瘤抗原？）积累的反应，或者是细胞免疫紊乱。
