Gehr M K, Chopra S, Chung T J, Hamburger R J
Arch Intern Med. 1982 Aug;142(8):1554-6.
Polyarteritis nodosa developed in one of 34 patients undergoing long-term maintenance hemodialysis with persistent hepatitis B surface antigenemia. Exacerbation of the baseline hypertension and progressive peripheral neuropathy during the recovery phase of hepatitis B surface antigen hepatitis were the initial features. Poor response to aggressive corticosteroid and immunosuppressive therapy in this patient was in contrast to recent experience in patients undergoing long-term hemodialysis and the general population.
在34例长期维持性血液透析且持续存在乙肝表面抗原血症的患者中,有1例发生了结节性多动脉炎。乙肝表面抗原性肝炎恢复期基线高血压的加重和进行性周围神经病变是最初的特征。该患者对积极的皮质类固醇和免疫抑制治疗反应不佳,这与长期血液透析患者和普通人群的近期经验形成对比。