钠离子在膜制剂和可溶制剂中调节激动剂和拮抗剂与人类血小板α2-肾上腺素能受体的相互作用。 - Suppr

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超能文献

Sodium ion modulates agonist and antagonist interactions with the human platelet alpha 2-adrenergic receptor in membrane and solubilized preparations.

作者信息

Limbird L E, Speck J L, Smith S K

出版信息

Mol Pharmacol. 1982 May;21(3):609-17.

PMID:6125876

Abstract

摘要

相似文献

Sodium ion modulates agonist and antagonist interactions with the human platelet alpha 2-adrenergic receptor in membrane and solubilized preparations.钠离子在膜制剂和可溶制剂中调节激动剂和拮抗剂与人类血小板α2-肾上腺素能受体的相互作用。

Mol Pharmacol. 1982 May;21(3):609-17.

Solubilization of human platelet alpha-adrenergic receptors: evidence for agonist-promoted receptor-effector association.人血小板α-肾上腺素能受体的增溶作用：激动剂促进受体-效应器缔合的证据。

Adv Cyclic Nucleotide Res. 1981;14:189-98.

Apparent "down-regulation" of human platelet alpha 2-adrenergic receptors is due to retained agonist.人类血小板α2 - 肾上腺素能受体的明显“下调”是由于激动剂的留存。

Mol Pharmacol. 1982 Jan;21(1):36-43.

N-ethylmaleimide, elevated temperature, and digitonin solubilization eliminate guanine nucleotide but not sodium effects on human platelet alpha 2-adrenergic receptor-agonist interactions.N-乙基马来酰亚胺、高温和洋地黄皂苷增溶作用消除了鸟嘌呤核苷酸对人血小板α2-肾上腺素能受体-激动剂相互作用的影响，但未消除钠的影响。

J Cyclic Nucleotide Protein Phosphor Res. 1983;9(3):191-201.

Sodium inhibits both adenylate cyclase and high-affinity 3H-labeled p-aminoclonidine binding to alpha 2-adrenergic receptors in purified human platelet membranes.钠可抑制纯化的人血小板膜中的腺苷酸环化酶以及高亲和力的3H标记的对氨基可乐定与α2 - 肾上腺素能受体的结合。

Mol Pharmacol. 1982 May;21(3):600-8.

The alpha 2-adrenergic receptor: multiple affinity states and regulation of a receptor inversely coupled to adenylate cyclase.α2-肾上腺素能受体：多种亲和力状态以及与腺苷酸环化酶反向偶联的受体的调节。

Adv Biochem Psychopharmacol. 1983;36:53-72.

Alpha-adrenergic stimulation of phosphatidylinositol synthesis in human platelets as an alpha-2 effect secondary to platelet aggregation.α-肾上腺素能刺激人血小板中磷脂酰肌醇的合成，作为血小板聚集继发的α-2效应。

J Cell Biochem. 1982;18(2):213-20. doi: 10.1002/jcb.1982.240180208.

Effects of alpha- and beta-adrenergic antagonist on epinephrine-induced aggregation and intracellular free calcium concentration in human platelets.α-和β-肾上腺素能拮抗剂对肾上腺素诱导的人血小板聚集及细胞内游离钙浓度的影响。

Biochem Biophys Res Commun. 1994 Jul 29;202(2):1069-75. doi: 10.1006/bbrc.1994.2037.

alpha-Noradrenergic receptors in the brain: differential effects of sodium on binding of [3H]agonists and [3H]antagonists.大脑中的α-去甲肾上腺素能受体：钠对[3H]激动剂和[3H]拮抗剂结合的不同影响。

Brain Res. 1978 Jan 27;140(2):378-84. doi: 10.1016/0006-8993(78)90472-9.

Agonist-specific effects of guanine nucleotides on alpha-adrenergic receptors in human platelets.鸟嘌呤核苷酸对人血小板α-肾上腺素能受体的激动剂特异性作用。

Mol Pharmacol. 1979 Jul;16(1):61-8.

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Pflugers Arch. 2003 Mar;445(6):716-20. doi: 10.1007/s00424-002-1002-y. Epub 2003 Jan 18.

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Endocrine. 2002 Nov;19(2):147-54. doi: 10.1385/ENDO:19:2:147.

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