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[大动脉炎中的动脉瘤]

[Aneurysms in Takayasu disease].

作者信息

Touré M K, Pasquier G, Herreman F, Bonnin A, Fouchard J, Houille F

出版信息

Arch Mal Coeur Vaiss. 1982 Jun;75(6):695-700.

PMID:6126166
Abstract

Takayashu's inflammatory panarteritis essentially results in stenotic lesions of the supra aortic axes and the collateral vessels of the abdominal aorta. Fusiform, segmental post-stenotic dilatation is commonly observed. Three particular types of aneurysms are described, each illustrated by a case report: --aneurysm of the ascending aorta causing severe aortic regurgitation by dilatation of the aortic ring: the diagnosis of Takayashu's disease was made in a young West Indian female on the evidence of associated aortic lesions and calcification of the descending thoracic aorta. The patient underwent replacement of the ascending aorta and aortic valve replacement. This form is very rare, although mild aortic regurgitation in Takayashu's disease has been reported in about ten cases by different workers; --large saccular aortic aneurysm. This lesion of the descending thoracic aorta with parietal calcification and without intrasaccular thrombosis was associated with a long, irregular stenosis of the paroxismal segment of the aorta, giving rise to signs of coarctation, and with multiple stenoses of the supra-aortic axes in a 31 year old Algerian. Surgical cure was realised by occluding the orifice in order to avoid replacing the aorta at the origin of the main medullary arteries. An ascending aorta-abdominal aorta bypass was performed at the same time, together with correction of the stenoses of the supra-aortic vessels. A few similar cases of large succular aneurysms of the thoracic or abdominal aorta or of the large collateral vessels have previously been described; --pseudo-aneurysm due to arterial rupture and formation of a large hematoma. A 20 year old Algerian presented with a polylobulated saccular aneurysm of the superficial femoral artery in the femoral triangle. Several stenotic lesions typical of Takayashu's disease (including a particularly rare stenosis of the contra lateral superficial femoral artery) were associated. At surgery, the lesion was found to be a pseudo-aneurysm with no true arterial wall on histological examination. The role of an infective endarteritis is discussed and excluded. This type of lesion does not appear to have been previously reported. These three varieties of aneurysm were the presenting signs of Takayashu's disease in the cases reported.

摘要

高安氏炎性全动脉炎主要导致主动脉弓上分支及腹主动脉侧支血管出现狭窄性病变。常可见梭形、节段性狭窄后扩张。本文描述了三种特殊类型的动脉瘤,每个类型均有病例报告说明:——升主动脉瘤因主动脉环扩张导致严重主动脉瓣关闭不全:一名年轻的西印度女性患者,根据其相关主动脉病变及降主动脉钙化的证据,诊断为高安氏病。该患者接受了升主动脉置换及主动脉瓣置换手术。这种类型非常罕见,尽管不同研究者曾报道过约10例高安氏病合并轻度主动脉瓣关闭不全的病例;——巨大囊状主动脉瘤。一名31岁的阿尔及利亚患者,其降主动脉病变表现为壁层钙化、无囊内血栓形成的巨大囊状动脉瘤,同时伴有主动脉阵发性节段的长段不规则狭窄,出现了缩窄体征,以及主动脉弓上分支多处狭窄。通过闭塞开口实现了手术治愈,以避免在主要髓动脉起始处置换主动脉。同时进行了升主动脉 - 腹主动脉旁路手术,并矫正了主动脉弓上血管的狭窄。此前曾描述过一些类似的胸主动脉或腹主动脉或大侧支血管巨大囊状动脉瘤病例;——因动脉破裂和形成巨大血肿导致的假性动脉瘤。一名20岁的阿尔及利亚患者,在股三角区出现股浅动脉多叶状囊状动脉瘤。伴有高安氏病典型的多处狭窄病变(包括对侧股浅动脉一处特别罕见的狭窄)。手术时发现该病变为假性动脉瘤,组织学检查未见真正的动脉壁。文中讨论并排除了感染性心内膜炎的作用。这种类型的病变此前似乎未见报道。在这些报告的病例中,这三种动脉瘤类型均为高安氏病的首发体征。

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