特非那定与马来酸氯苯那敏治疗常年性鼻炎的对照试验。
Controlled trial of terfenadine and chlorpheniramine maleate in perennial rhinitis.
作者信息
Brostoff J, Lockhart J D
出版信息
Postgrad Med J. 1982 Jul;58(681):422-3. doi: 10.1136/pgmj.58.681.422.
Abstract
A double-blind clinical trial in 60 patients with perennial rhinitis was conducted to compare the efficacy and side effects of two antihistamines, terfenadine and chlorpheniramine maleate, and placebo. There was no statistically significant difference in response between active treatments and placebo. Although side effects were more frequent with chlorpheniramine this also was not statistically significant.
摘要
对60例常年性鼻炎患者进行了一项双盲临床试验，以比较两种抗组胺药（特非那定和马来酸氯苯那敏）及安慰剂的疗效和副作用。活性治疗组与安慰剂组在反应上无统计学显著差异。虽然氯苯那敏的副作用更常见，但这也无统计学显著意义。
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本文引用的文献
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Ann Allergy. 1980 Feb;44(2):71-5.
2
Performance studies with antihistamines.抗组胺药的性能研究。
Br J Clin Pharmacol. 1978 Jul;6(1):31-5. doi: 10.1111/j.1365-2125.1978.tb01678.x.
3
Some clinical pharmacological studies with terfenadine, a new antihistamine drug.一些关于新型抗组胺药特非那定的临床药理学研究。
Br J Clin Pharmacol. 1978 Jul;6(1):25-9. doi: 10.1111/j.1365-2125.1978.tb01677.x.
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