Svobodová J, Blaskovic D, Mistríková J
Acta Virol. 1982 Jul;26(4):256-63.
Sixteen cell cultures of different origin (bird, rodents, carnivores, pigs, monkey, man) reproduced five strains of herpesviruses isolated from small free living rodents Apodemus flavicollis and Clethrionomys glareolus revealing cytopathic changes typical for members of the family Herpesviridae. The virus titres in different cell cultures ranged from 10(2) to 10(7) TCD50 per ml. The growth curves of two isolates originating from both animal species resembled to those obtained with human herpesviruses type 1 and 2, pseudorabies virus and guinea pig herpes-like virus (Hsiung-Kaplow) in identical cell cultures. Mouse cytomegalovirus was grown practically in mouse embryo fibroblasts only. The five isolates from free living small rodents were classified according to cytopathic changes and growth characteristics in different cell cultures as members of the subfamily Alphaherpesvirinae.
来自不同来源（鸟类、啮齿动物、食肉动物、猪、猴子、人类）的16种细胞培养物繁殖出了从野生小家鼠和黄喉姬鼠中分离出的5株疱疹病毒，呈现出疱疹病毒科成员典型的细胞病变变化。不同细胞培养物中的病毒滴度范围为每毫升10(2)至10(7)个组织培养感染剂量50（TCD50）。源自这两种动物的两株分离株的生长曲线类似于在相同细胞培养物中用人疱疹病毒1型和2型、伪狂犬病病毒和豚鼠疱疹样病毒（熊-卡普洛病毒）所获得的生长曲线。小鼠巨细胞病毒实际上仅在小鼠胚胎成纤维细胞中生长。根据不同细胞培养物中的细胞病变变化和生长特性，将从野生小型啮齿动物中分离出的5株分离株归类为α疱疹病毒亚科的成员。
