大鼠网织红细胞β-肾上腺素能受体激动剂结合特性 - Suppr

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Properties of agonist binding at the beta-adrenoceptor of the rat reticulocyte.

作者信息

Wiemer G, Wellstein A, Palm D, von Hattingberg H M, Brockmeier D

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 1982 Oct;321(1):11-9. doi: 10.1007/BF00586342.

DOI:10.1007/BF00586342

PMID:6128680

Abstract

摘要

相似文献

Properties of agonist binding at the beta-adrenoceptor of the rat reticulocyte.大鼠网织红细胞β-肾上腺素能受体激动剂结合特性

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Comparison of specificity of agonist and antagonist radioligand binding to beta adrenergic receptors.激动剂和拮抗剂放射性配体与β肾上腺素能受体结合特异性的比较。

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Characterization of radiolabeled agonist binding to beta-adrenergic receptors in mammalian tissues.

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Beta-adrenoceptor sites in maturing red blood cells of the rat: differing development of agonist and antagonist binding.大鼠成熟红细胞中的β-肾上腺素能受体位点：激动剂和拮抗剂结合的不同发育情况。

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Characteristics of beta-adrenergic-agonist binding to rat adipocyte membranes. Evidence that (+/-)-[3H]hydroxybenzylisoproterenol interacts selectively with the adipocyte beta-adrenergic receptors.β-肾上腺素能激动剂与大鼠脂肪细胞膜结合的特性。（±）-[³H]羟基苄基异丙肾上腺素与脂肪细胞β-肾上腺素能受体选择性相互作用的证据。

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Properties of beta-adrenoceptor sites in metabolizing and nonmetabolizing rat reticulocytes and in resealed reticulocyte ghosts.代谢型和非代谢型大鼠网织红细胞以及重封网织红细胞血影中β-肾上腺素能受体位点的特性

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Cell metabolism affects the density of beta-adrenergic receptors in intact rat reticulocytes.

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Homogeneity of beta 2-adrenoceptors on rat erythrocytes and reticulocytes. A comparison with heterogeneous rat lung beta-adrenoceptors.大鼠红细胞和网织红细胞上β2 -肾上腺素能受体的同质性。与异质性大鼠肺β -肾上腺素能受体的比较。

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Selective alteration in high affinity agonist binding: a mechanism of beta-adrenergic receptor desensitization.高亲和力激动剂结合的选择性改变：β-肾上腺素能受体脱敏的一种机制。

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[3H]dihydroalprenolol binding in the rat brainstem.大鼠脑干中[3H]二氢阿普洛尔结合

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Simple and reliable radioreceptor assay for beta-adrenoceptor antagonists and active metabolites in native human plasma.用于检测天然人血浆中β-肾上腺素能受体拮抗剂及其活性代谢物的简单可靠的放射受体分析法。

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Penbutolol: beta-adrenoceptor interaction and the time course of plasma concentrations explain its prolonged duration of action in man.喷布洛尔：β-肾上腺素能受体相互作用及血浆浓度的时程解释了其在人体中作用持续时间延长的原因。

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Receptor binding of propranolol is the missing link between plasma concentration kinetics and the effect-time course in man.普萘洛尔的受体结合是人体血浆浓度动力学与效应时程之间缺失的环节。

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Agonist binding at alpha 2-adrenoceptors of human platelets using 3H-UK-14,304: regulation by Gpp(NH)p and cations.使用³H-UK-14,304研究激动剂与人血小板α₂-肾上腺素能受体的结合：Gpp(NH)p和阳离子的调节作用

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本文引用的文献

Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。

J Biol Chem. 1951 Nov;193(1):265-75.

On the evaluation of the constants Vm and KM in enzyme reactions.关于酶促反应中常数Vm和KM的评估。

Science. 1952 Sep 26;116(3013):329-31. doi: 10.1126/science.116.3013.329.

A minor component of the binding of [3H]guanyl-5'-yl imidodiphosphate to cardiac membranes associated with the activation of adenylate cyclase.[3H]鸟苷-5'-基亚氨基二磷酸与心肌膜的结合中与腺苷酸环化酶激活相关的一个次要成分。

J Biol Chem. 1981 Aug 10;256(15):7925-31.

Activation and attenuation of adenylate cyclase. The role of GTP-binding proteins as macromolecular messengers in receptor--cyclase coupling.腺苷酸环化酶的激活与衰减。GTP结合蛋白作为受体 - 环化酶偶联中大分子信使的作用。

Biochem J. 1981 Apr 1;195(1):1-13. doi: 10.1042/bj1950001.

Alternative explanation for the apparent "two-step" binding kinetics of high-affinity racemic antagonist radioligands.高亲和力外消旋拮抗剂放射性配体明显的“两步”结合动力学的另一种解释。

Mol Pharmacol. 1981 May;19(3):509-12.

Beta-adrenergic activity of (+/-)-hydroxybenzylisoproterenol in isolated rat fat cells and hepatocytes.（±）-羟基苄基异丙肾上腺素在分离的大鼠脂肪细胞和肝细胞中的β-肾上腺素能活性。

Biochim Biophys Acta. 1981 Mar 5;673(2):203-16.

Differential regulation of the alpha 2-adrenergic receptor by Na+ and guanine nucleotides.钠离子和鸟嘌呤核苷酸对α2-肾上腺素能受体的差异性调节

Nature. 1980 Dec 25;288(5792):709-11. doi: 10.1038/288709a0.

Adrenergic receptors.肾上腺素能受体

Adv Cyclic Nucleotide Res. 1980;12:37-47.

A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.三元复合物模型解释了与腺苷酸环化酶偶联的β-肾上腺素能受体的激动剂特异性结合特性。

J Biol Chem. 1980 Aug 10;255(15):7108-17.

Modulation of beta-adrenergic agonist binding by guanylnucleotides in avian erythrocytes.鸟红细胞中鸟苷酸对β-肾上腺素能激动剂结合的调节作用。

FEBS Lett. 1980 Jun 16;115(1):113-7. doi: 10.1016/0014-5793(80)80738-1.

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