Diaz G, Orzalesi N, Fossarello M, Carta S, Del Fiacco G
Exp Eye Res. 1982 Aug;35(2):99-106. doi: 10.1016/s0014-4835(82)80058-4.
Coated pits (CPs) and coated vesicles (CVs) were investigated in the trabecular meshwork of man and rabbit. In both man and rabbit CPs and CVs appear to be randomly distributed throughout the trabecular tissue. CVs are located in the peripheral cytoplasm of the trabecular endothelial cells and show an average diameter of 0 . 16 micron. The ratio between the number of CPs and CVs ranges from 0 . 53 (rabbit) to 0 . 6 (man). The number of CPs and CVs is higher in rabbit than in man. Consequently, the overall CPs surface and CVs volume density estimates are higher in rabbits, where CPs represent about 1% of the cell surface and CVs account for about 0 . 4% of the cell cytoplasm. In man these percentages are 0 . 46 and 0 . 17%, respectively. No significant changes of CPs and CVs were found in rabbits with corticosteroid-induced ocular hypertension. However, changes in length of boundary membrane of CPs, though not statistically significant, were accompanied by proportional changes in CVs diameter.
对人和兔的小梁网中的被覆小窝(CPs)和被覆小泡(CVs)进行了研究。在人和兔中,CPs和CVs似乎随机分布于整个小梁组织。CVs位于小梁内皮细胞的周边细胞质中,平均直径为0.16微米。CPs与CVs数量之比在0.53(兔)至0.6(人)之间。兔的CPs和CVs数量高于人。因此,兔的CPs总表面积和CVs体积密度估计值更高,其中CPs约占细胞表面的1%,CVs约占细胞质的0.4%。在人中,这些百分比分别为0.46%和0.17%。在皮质类固醇诱导的兔高眼压模型中,未发现CPs和CVs有显著变化。然而,CPs边界膜长度的变化虽然无统计学意义,但伴随着CVs直径的相应变化。