Andersch B
Int J Gynaecol Obstet. 1982 Dec;20(6):463-9. doi: 10.1016/0020-7292(82)90007-8.
The influence of different oral contraceptives on premenstrual complaints was examined in 191 randomly selected women from an urban population. Premenstrual depression and abdominal swelling was significantly more common in women taking oral contraceptives containing the progestogen component lynestrenol than those containing norgestrel. The reason for this difference is discussed. A deficiency of pyridoxine which affects tryptophan metabolism can explain the difference in premenstrual depression. However, it should be emphasized that the system which controls neuro-endocrine balance is extremely complicated and does not at the present time permit any definite conclusions regarding the influence of oral contraceptives on mental complaints.
在从城市人口中随机挑选的191名女性中，研究了不同口服避孕药对经前不适的影响。与服用含炔诺孕酮的口服避孕药的女性相比，服用含炔雌醇甲醚孕酮成分的口服避孕药的女性经前抑郁和腹部肿胀明显更为常见。文中讨论了这种差异的原因。影响色氨酸代谢的维生素B6缺乏可以解释经前抑郁的差异。然而，应该强调的是，控制神经内分泌平衡的系统极其复杂，目前无法就口服避孕药对精神不适的影响得出任何明确结论。
