Louv W C, Austin H, Perlman J, Alexander W J
Department of Epidemiology, University of Alabama, Birmingham.
Am J Obstet Gynecol. 1989 Feb;160(2):396-402. doi: 10.1016/0002-9378(89)90456-0.
Oral contraceptive users were compared with nonusers with respect to the rate of cervical infections by Chlamydia trachomatis and Neisseria gonorrhoeae. The comparison was adjusted for differences in demographic and behavioral characteristics between the two groups. The rates of infection among oral contraceptive users were increased by approximately 70% (statistically significant) for both pathogens. Cervical ectopy was implicated in the increased rate of chlamydia but not gonorrhea. Rates of gonorrheal infection differed significantly among oral contraceptive formulations; rates were higher for formulations containing more androgenic progestins.
就沙眼衣原体和淋病奈瑟菌引起的宫颈感染率而言，对口服避孕药使用者和非使用者进行了比较。针对两组人群在人口统计学和行为特征方面的差异进行了比较调整。对于这两种病原体，口服避孕药使用者的感染率均提高了约70%（具有统计学意义）。衣原体感染率的上升与宫颈外翻有关，但淋病并非如此。不同口服避孕药配方的淋病感染率存在显著差异；含有更多雄激素活性孕激素的配方感染率更高。
