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[大鼠嗅结节的递质组织化学]

[Transmitter histochemistry of the olfactory tubercle in the rat].

作者信息

Danner H, Pfister C, Morgenstern R

出版信息

J Hirnforsch. 1982;23(4):391-7.

PMID:6131093
Abstract

The tuberculum olfactorium of the adult rat was investigated by means of neurohistological, fluorescence histochemical and enzyme histochemical methods. Using the rapid Golgi impregnation technique, seven neuron types could be demonstrated which can clearly be differentiated according to morphological criteria. Using the glyoxylic acid techniques, strongly fluorescent dopamine fibers are, in different densities, visible within the various laminae. Kainic acid application into the ventral tegmental area is followed by a strikingly reduced, no more structurally associated dopamine fiber fluorescence. After DFP intoxication, only a small proportion of the neuron population of the tuberculum olfactorium does exhibit an AChE activity; the AChE containing neurons are different as to their size and shape. The findings presented here are discussed with respect to the attributability of histochemical findings to cytoarchitectural features of this brain area.

摘要

采用神经组织学、荧光组织化学和酶组织化学方法对成年大鼠的嗅结节进行了研究。运用快速高尔基浸染技术,可显示出七种神经元类型,根据形态学标准能够清晰区分。运用乙醛酸技术,在各层中可见不同密度的强荧光多巴胺纤维。向腹侧被盖区注射 kainic 酸后,多巴胺纤维荧光显著减弱,且不再有结构上的关联。DFP 中毒后,嗅结节中只有一小部分神经元群体表现出 AChE 活性;含 AChE 的神经元在大小和形状上有所不同。本文就组织化学结果与该脑区细胞结构特征的归因关系进行了讨论。

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