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[生物源性单胺在大鼠脑硬脑膜中的定位]

[Localization of biogenic monoamines in the dura mater of the rat brain].

作者信息

Motavkin P A, Karedina V S, Kozhevnikova T A

出版信息

Arkh Anat Gistol Embriol. 1985 May;88(5):11-6.

PMID:2862857
Abstract

Quantitative and qualitative composition of catecholamines (noradrenaline and dophamine) and indolalkylamines (serotonin and tryptamine) and their localization have been studied in cells and neural fibers of the rat dura mater. Luminiscent-cytophotometric and electron microscopic methods have revealed two types of cells depositing biogenic monoamines. As demonstrate the experiments with rausedil injection, monoaminocytes of the first type (mast cells) contain predominantly indolalkylamines and a small amount of dophamine. Monoaminocytes of the second type (chromaffin cells) synthesize mainly serotonin and, perhaps, tryptamine. In adrenergic neural fibers only noradrenaline has been found to be present.

摘要

已对大鼠硬脑膜的细胞和神经纤维中儿茶酚胺(去甲肾上腺素和多巴胺)、吲哚烷基胺(5-羟色胺和色胺)的定量和定性组成及其定位进行了研究。发光细胞光度法和电子显微镜方法已揭示出两种储存生物源性单胺的细胞类型。如用劳地洛尔注射实验所示,第一类单胺细胞(肥大细胞)主要含有吲哚烷基胺和少量多巴胺。第二类单胺细胞(嗜铬细胞)主要合成5-羟色胺,或许还合成色胺。在肾上腺素能神经纤维中,仅发现有去甲肾上腺素存在。

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