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神经递质、酶及药物对钙通道的调节作用

Calcium channel modulation by neurotransmitters, enzymes and drugs.

作者信息

Reuter H

出版信息

Nature. 1983;301(5901):569-74. doi: 10.1038/301569a0.

Abstract

Calcium channels in excitable membranes are of great importance for many cellular functions. Modulation of these channels by neurotransmitters and drugs regulates calcium influx into the cell and thereby alters the functional state of the cell. Recently it has become possible to measure properties of single calcium channels directly and to obtain evidence on mechanisms of their modulation.

摘要

可兴奋膜中的钙通道对许多细胞功能极为重要。神经递质和药物对这些通道的调节可控制钙离子流入细胞,从而改变细胞的功能状态。近来,已能够直接测量单个钙通道的特性,并获得有关其调节机制的证据。

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