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[痛性营养不良症的治疗]

[Treatment of algodystrophies].

作者信息

Delcambre B, Duquesnoy B, Baudens G, Cocheteux P, Thevenon A, Delfosse J M, Pouyol F

出版信息

Rev Rhum Mal Osteoartic. 1982 Dec;49(12):849-56.

PMID:6131528
Abstract

The first part of the article is a general review of the various drug treatments available for algodystrophy : purely symptomatic, analgesic treatment, vaso-active drugs, calcitonin. The major advance over the last few years has been the use of beta-blockers and calcitonin but, to date, only one double blind trial has been published. This study demonstrated the value of calcitonin after one month of treatment. The authors undertook a retrospective study of 651 cases and a prospective study of 91 cases and based their work on the evaluation of various treatments prescribed separately examining each therapeutic sequence rather than each individual case. Three treatments stood out by their frequent use : griseofulvin, calcitonin and beta-blockers. Each of these drugs was effective in more than 60 p. cent of cases. It is impossible, in such a study, to formulate a hierarchy of the various treatments. Only controlled studies will be able to establish their order of effectiveness. The results vary somewhat according to the site of the algodystrophy. The best therapeutic response is obtained in lesions involving the hip leading to a very favourable prognosis.

摘要

本文的第一部分是对可用于治疗痛性营养不良的各种药物疗法的综述

纯粹的对症、止痛治疗、血管活性药物、降钙素。过去几年的主要进展是使用了β受体阻滞剂和降钙素,但迄今为止,仅发表了一项双盲试验。这项研究证明了治疗一个月后降钙素的价值。作者对651例病例进行了回顾性研究,对91例病例进行了前瞻性研究,其工作基于对单独开具的各种治疗方法的评估,审查每个治疗顺序而非每个单独病例。三种治疗方法因其频繁使用而突出:灰黄霉素、降钙素和β受体阻滞剂。这些药物中的每一种在超过60%的病例中都有效。在这样的研究中,不可能对各种治疗方法进行排序。只有对照研究才能确定它们的有效性顺序。根据痛性营养不良的部位,结果会有所不同。在涉及髋关节的病变中获得的治疗反应最佳,预后非常良好。

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