Cherot A, Amor B
Rev Rhum Mal Osteoartic. 1983 Feb;50(2):95-7.
Three randomised therapeutic protocols were studied: thyrocalcitonin, beta-blockers and the combination of Grisefuline + Penthonium, in a group of 95 cases of algodystrophy (64 women, 31 men). These cases were divided into four groups: upper limb, lower limb, "recent" or "long-standing". The results were assessed after one month of treatment. A positive result was defined as being an improvement of more than 50 p. cent of the clinical subjective and objective criteria; less than that, the activity is uncertain or nil. Comparison of the results did not reveal any statistically significant difference between the three proposed treatments, whether we consider the whole group of patients or each sub-group separately (overall positive results: Calsyn 100 = 53 p. cent, Visken = 42,5 p. cent, Grisefuline + Penthonium = 53 p. cent). The important role played by rehabilitation must be stressed. It should be discontinued during the acute phase and instituted in the later phase. Cure is obtained after an average of 4-5 months of treatment. 10 patients were left with major trophic sequelae after 2 years of the disease; all involve the hand.
对95例营养障碍患者（64名女性，31名男性）研究了三种随机治疗方案：降钙素、β受体阻滞剂以及灰黄霉素+喷托铵的组合。这些病例分为四组：上肢组、下肢组、“近期”组或“长期”组。治疗一个月后评估结果。阳性结果定义为临床主观和客观标准改善超过50%；低于该水平，则疗效不确定或无效。无论将所有患者视为一组还是分别考虑每个亚组，三种治疗方案之间的结果比较均未显示出任何统计学上的显著差异（总体阳性结果：降钙素100=53%，吲哚洛尔=42.5%，灰黄霉素+喷托铵=53%）。必须强调康复所起的重要作用。在急性期应停止康复，在后期开始进行。平均治疗4 - 5个月后可治愈。10名患者在患病2年后留下了严重的营养后遗症；均累及手部。
