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O6血清群产肠毒素大肠杆菌(ETEC)对牛红细胞的血凝作用:糖缀合物受体异质性的证据

Haemagglutination of bovine erythrocytes by enterotoxigenic E. coli (ETEC) of O 6 serogroup: evidence for glycoconjugate receptor heterogeneity.

作者信息

Faris A, Sellei J, Lindahl M, Wadström T

出版信息

Zentralbl Bakteriol Mikrobiol Hyg A Med Mikrobiol Infekt Parasitol. 1982 Nov;253(2):175-82.

PMID:6131562
Abstract

Five strains of enterotoxigenic E. coli (ETEC) producing fimbrial antigens which cause mannose-resistant haemagglutination of bovine erythrocytes (MRHA+bov) were selected among a collection of ETEC strains of the O 6 serogroup with CFA/II-like fimbrial haemagglutinins for this study. Our findings indicate that the MRHA reaction of bovine erythrocytes with these five strains reacted differently in a reproducible manner with erythrocytes from different bovine individuals. However, the complex heterogeneity of bovine erythrocyte antigens has not made it possible to relate specific blood group antigen(s) with the MRHA reaction with these different MRHA+bov ETEC strains. We conclude that bovine erythrocytes from individual animals must be tested with a battery of ETEC strains causing MRHA+bov before use in screening for CFA/II-like haemagglutinins.

摘要

从一组具有CFA/II样菌毛血凝素的O 6血清群产肠毒素大肠杆菌(ETEC)菌株中,挑选出5株产生能引起牛红细胞甘露糖抗性血凝反应(MRHA+bov)的菌毛抗原的ETEC菌株用于本研究。我们的研究结果表明,这5株菌株与牛红细胞的MRHA反应,在与不同牛个体的红细胞反应时呈现出可重复的不同反应方式。然而,牛红细胞抗原的复杂异质性使得无法将特定血型抗原与这些不同的MRHA+bov ETEC菌株的MRHA反应联系起来。我们得出结论,在用于筛选CFA/II样血凝素之前,必须用一组能引起MRHA+bov的ETEC菌株对单个动物的牛红细胞进行检测。

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1
Haemagglutination of bovine erythrocytes by enterotoxigenic E. coli (ETEC) of O 6 serogroup: evidence for glycoconjugate receptor heterogeneity.O6血清群产肠毒素大肠杆菌(ETEC)对牛红细胞的血凝作用:糖缀合物受体异质性的证据
Zentralbl Bakteriol Mikrobiol Hyg A Med Mikrobiol Infekt Parasitol. 1982 Nov;253(2):175-82.
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引用本文的文献

1
Purification and characterization of CS2, a sialic acid-specific haemagglutinin of enterotoxigenic Escherichia coli.产肠毒素大肠杆菌的唾液酸特异性血凝素CS2的纯化与特性分析
Biochem J. 1988 Oct 1;255(1):105-11. doi: 10.1042/bj2550105.
2
Colonization factors of enterotoxigenic Escherichia coli isolated from children with diarrhea in Argentina.从阿根廷腹泻儿童中分离出的产肠毒素大肠杆菌的定植因子。
J Clin Microbiol. 1991 Sep;29(9):1893-8. doi: 10.1128/jcm.29.9.1893-1898.1991.