Yamashita M, Koishi K, Yamaya R, Tsubo T, Matsuki A, Oyama T
Can Anaesth Soc J. 1983 Mar;30(2):179-84. doi: 10.1007/BF03009349.
The anaesthetic management of four paediatric patients with the Prader-Willi syndrome is reported. The syndrome is characterized by obesity, mental retardation, genital hypoplasia, hypotonia, and diabetes mellitus. All patients were anaesthetized with halothane. Succinylcholine or pancuronium were used for muscle relaxation, without evidence of abnormal response. Common anaesthetic difficulties in this syndrome are obesity, hypotonia, disturbance in thermoregulation, arrhythmias, diabetes mellitus and convulsions.
本文报告了4例普拉德-威利综合征患儿的麻醉处理情况。该综合征的特征为肥胖、智力发育迟缓、生殖器发育不全、肌张力减退和糖尿病。所有患儿均采用氟烷麻醉。使用琥珀酰胆碱或泮库溴铵进行肌肉松弛，未发现异常反应。该综合征常见的麻醉困难包括肥胖、肌张力减退、体温调节障碍、心律失常、糖尿病和惊厥。
