• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

用于治疗直立性低血压的交感神经假体

Sympathetic neural prosthesis for managing orthostatic hypotension.

作者信息

Polinsky R J, Samaras G M, Kopin I J

出版信息

Lancet. 1983 Apr 23;1(8330):901-4. doi: 10.1016/s0140-6736(83)91329-6.

DOI:10.1016/s0140-6736(83)91329-6
PMID:6132222
Abstract

A prototype electromechanical analogue of the sympathetic division of the baroreceptor reflex arc was used to maintain blood pressure automatically in two patients with neurogenic orthostatic hypotension. The device prevented significant and sustained reductions in mean blood pressure when the patients were tilted up to 85 degrees. Upon achieving the preset mean blood pressure, the device maintained this pressure with a standard error of less than 2 mm Hg. Similar results were obtained when the patients were walking. The device did not cause supine hypertension during the trials.

摘要

使用压力感受器反射弧交感神经部分的机电模拟原型,对两名神经源性直立性低血压患者进行血压自动维持。当患者倾斜至85度时,该装置可防止平均血压出现显著且持续的下降。达到预设平均血压后,该装置维持此血压,标准误差小于2毫米汞柱。患者行走时也获得了类似结果。试验期间该装置未引起仰卧位高血压。

相似文献

1
Sympathetic neural prosthesis for managing orthostatic hypotension.用于治疗直立性低血压的交感神经假体
Lancet. 1983 Apr 23;1(8330):901-4. doi: 10.1016/s0140-6736(83)91329-6.
2
Bionic baroreceptor corrects postural hypotension in rats with impaired baroreceptor.仿生压力感受器可纠正压力感受器受损大鼠的体位性低血压。
Circulation. 2012 Sep 4;126(10):1278-85. doi: 10.1161/CIRCULATIONAHA.112.108357. Epub 2012 Jul 31.
3
Neurogenic orthostatic hypotension: roles of norepinephrine deficiency in its causes, its treatment, and future research directions.神经源性直立性低血压:去甲肾上腺素缺乏在其病因、治疗及未来研究方向中的作用
Curr Med Res Opin. 2015 Nov;31(11):2095-104. doi: 10.1185/03007995.2015.1087988. Epub 2015 Oct 13.
4
Diagnosing and treating neurogenic orthostatic hypotension in primary care.在初级保健中诊断和治疗神经源性直立性低血压
Postgrad Med. 2015;127(7):702-15. doi: 10.1080/00325481.2015.1050340. Epub 2015 May 27.
5
Management of neurogenic orthostatic hypotension in patients with autonomic failure.自主神经衰竭患者神经源性直立性低血压的管理。
Drugs. 2013 Aug;73(12):1267-79. doi: 10.1007/s40265-013-0097-0.
6
Excessive gravitational blood pooling caused by impaired venous tone is the predominant non-cardiac mechanism of orthostatic intolerance.静脉张力受损导致的过度重力性血液淤积是体位性不耐受的主要非心脏机制。
Clin Sci (Lond). 1996 Apr;90(4):277-85. doi: 10.1042/cs0900277.
7
Investigation and treatment of autonomic circulatory failure.自主循环衰竭的调查与治疗。
Curr Opin Neurol Neurosurg. 1993 Aug;6(4):537-43.
8
Initial and delayed circulatory responses to orthostatic stress in normal humans and in subjects with orthostatic intolerance.正常人和体位性不耐受受试者对体位性应激的初始和延迟循环反应。
Int Angiol. 1992 Jan-Mar;11(1):69-82.
9
Clonidine raises blood pressure in severe idiopathic orthostatic hypotension.可乐定可使严重特发性直立性低血压患者的血压升高。
Am J Med. 1983 Feb;74(2):193-200. doi: 10.1016/0002-9343(83)90607-1.
10
Localization of lesion in patients with idiopathic orthostatic hypotension.特发性直立性低血压患者病变的定位
Br Heart J. 1975 Aug;37(8):868-72. doi: 10.1136/hrt.37.8.868.

引用本文的文献

1
Homeostatic systems, biocybernetics, and autonomic neuroscience.稳态系统、生物控制论与自主神经科学。
Auton Neurosci. 2017 Dec;208:15-28. doi: 10.1016/j.autneu.2017.09.001. Epub 2017 Sep 5.
2
Management of neurogenic orthostatic hypotension in patients with autonomic failure.自主神经衰竭患者神经源性直立性低血压的管理。
Drugs. 2013 Aug;73(12):1267-79. doi: 10.1007/s40265-013-0097-0.
3
Temporary elimination of orthostatic hypotension by norepinephrine infusion.去甲肾上腺素输注消除直立性低血压。
Clin Auton Res. 2012 Dec;22(6):303-6. doi: 10.1007/s10286-012-0176-4. Epub 2012 Sep 16.
4
Neurocardiology: therapeutic implications for cardiovascular disease.神经心脏病学:心血管疾病的治疗意义。
Cardiovasc Ther. 2012 Apr;30(2):e89-106. doi: 10.1111/j.1755-5922.2010.00244.x. Epub 2010 Nov 25.