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各种亚硝基脲的化疗研究：预防乙基亚硝基脲诱发的神经系统肿瘤的发生

Chemotherapy studies of various nitrosoureas: prevention of development of ethylnitrosourea-induced tumors in the nervous system.

作者信息

Paoletti P, Giordana M T, Pezzotta S, Schiffer D

出版信息

Natl Cancer Inst Monogr. 1977 Dec;46:161-2.

PMID:613226
Abstract

Of four nitrosoureas administered to F344 rats that were offspring of mothers treated with ethylnitrosourea during pregnancy, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea and its methyl derivative were particularly effective in blocking tumor development.

摘要

在对孕期经乙基亚硝基脲处理的母鼠所产的F344大鼠给予四种亚硝基脲后，1-(2-氯乙基)-3-环己基-1-亚硝基脲及其甲基衍生物在阻断肿瘤发生方面特别有效。

相似文献

1
Chemotherapy studies of various nitrosoureas: prevention of development of ethylnitrosourea-induced tumors in the nervous system.各种亚硝基脲的化疗研究：预防乙基亚硝基脲诱发的神经系统肿瘤的发生
Natl Cancer Inst Monogr. 1977 Dec;46:161-2.
2
Congenital malformations of the central nervous system and transplacental carcinogenesis: modification of ethylnitrosourea-induced brain tumors in rats by pretreatment with methylazoxymethanol.
Int J Biol Res Pregnancy. 1982;3(3):93-8.
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The effect of BCNU, CCNU and MeCCNU in the prevention of the development of tumors of the nervous system.卡莫司汀、洛莫司汀和司莫司汀在预防神经系统肿瘤发生方面的作用。
Pharmacol Res Commun. 1975 Feb;07(1):49-53. doi: 10.1016/s0031-6989(75)80029-4.
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[Experimental brain neoplasm induced by ethylnitrosourea. Frequency of incidence and neurological manifestation in rats].[乙基亚硝基脲诱导的实验性脑肿瘤。大鼠的发病率及神经学表现]
No To Shinkei. 1976 May;28(5):439-49.
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J Natl Cancer Inst. 1978 Aug;61(2):365-74.
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Prenatal multicarcinogenesis by ethylnitrosourea in mice.
Cancer Res. 1977 Jun;37(6):1822-8.
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Anticancer Res. 1982 Jan-Apr;2(1-2):79-87.
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[Lysosomal enzymes in nitrosamine induced nervous system tumors of rats (author's transl)].[亚硝胺诱导大鼠神经系统肿瘤中的溶酶体酶（作者译）]
No Shinkei Geka. 1974 Sep;2(9):629-36.
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Chemotherapeutic effects of some alkylating derivatives of nitrosourea on the development of tumors transplacentally induced in rats by ENU.
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