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Chemotherapeutic effects of some alkylating derivatives of nitrosourea on the development of tumors transplacentally induced in rats by ENU.

作者信息

Schiffer D, Giordana M T, Pezzotta S, Paoletti P

出版信息

Acta Neuropathol. 1976 Jan 31;34(1):21-31. doi: 10.1007/BF00684940.

Abstract

The application of BCNU, CCNU and MeCCNU has been shown to greatly reduce the number of tumors induced in rats by transplacentally administered ENU and to inhibit the full development of tumor proliferation. Moreover, no neurinomas appeared after treatment with CCNU. The application of GCNU proved to be much less effective. Our statistics in the form of tables showing these findings are included and discussed.

摘要

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