Calne D B
Can J Neurol Sci. 1983 Feb;10(1):11-5. doi: 10.1017/s0317167100044498.
Since the introduction of levodopa therapy, there have been major advances in the understanding and treatment of Parkinson's disease. However, the problems and limitations associated with this form of treatment are now becoming increasingly apparent. This article reviews some of the current knowledge concerning the etiology and pathophysiology of Parkinson's disease and discusses some practical approaches to drug therapy.
自从左旋多巴疗法问世以来，在帕金森病的认识和治疗方面取得了重大进展。然而，这种治疗方式相关的问题和局限性现在正变得越来越明显。本文回顾了一些关于帕金森病病因和病理生理学的当前知识，并讨论了药物治疗的一些实用方法。
