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家鸡体内空肠和回肠对葡萄糖和缬氨酸吸收功能的比较——一种估算家鸡真实米氏常数(Km)和最大转运速率(Jmax)的技术

Comparison of jejunal and ileal absorptive functions for glucose and valine in vivo--a technique for estimating real Km and Jmax in the domestic fowl.

作者信息

Levin R J, Mitchell M A, Barber D C

出版信息

Comp Biochem Physiol A Comp Physiol. 1983;74(4):961-6. doi: 10.1016/0300-9629(83)90377-8.

Abstract
  1. A technique is described that enables the kinetic characterisation of the saturable absorption mechanisms in the chicken jejunum and ileum for glucose and valine in vivo (after correction for non-saturating components and unstirred layers) by estimation of real Km and Jmax. 2. In the ileum both nutrients have lower real Km and higher Jmax values than in the jejunum indicating, at least for hexose and amino acids, that the ileal enterocytes are functionally equipped and anatomically well-sited to fulfil the role of scavengers of the small intestine.
摘要
  1. 本文描述了一种技术,该技术能够通过估算实际的米氏常数(Km)和最大反应速率(Jmax),在体内对鸡空肠和回肠中葡萄糖和缬氨酸的饱和吸收机制进行动力学表征(校正非饱和成分和未搅动层之后)。2. 回肠中两种营养物质的实际Km均低于空肠,而Jmax则高于空肠,这表明至少对于己糖和氨基酸而言,回肠肠上皮细胞在功能上具备条件,且在解剖位置上也适宜充当小肠清道夫的角色。

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