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家鸡体内空肠和回肠对葡萄糖和缬氨酸吸收功能的比较——一种估算家鸡真实米氏常数(Km)和最大转运速率(Jmax)的技术

Comparison of jejunal and ileal absorptive functions for glucose and valine in vivo--a technique for estimating real Km and Jmax in the domestic fowl.

作者信息

Levin R J, Mitchell M A, Barber D C

出版信息

Comp Biochem Physiol A Comp Physiol. 1983;74(4):961-6. doi: 10.1016/0300-9629(83)90377-8.

DOI:10.1016/0300-9629(83)90377-8
PMID:6132746
Abstract
  1. A technique is described that enables the kinetic characterisation of the saturable absorption mechanisms in the chicken jejunum and ileum for glucose and valine in vivo (after correction for non-saturating components and unstirred layers) by estimation of real Km and Jmax. 2. In the ileum both nutrients have lower real Km and higher Jmax values than in the jejunum indicating, at least for hexose and amino acids, that the ileal enterocytes are functionally equipped and anatomically well-sited to fulfil the role of scavengers of the small intestine.
摘要
  1. 本文描述了一种技术,该技术能够通过估算实际的米氏常数(Km)和最大反应速率(Jmax),在体内对鸡空肠和回肠中葡萄糖和缬氨酸的饱和吸收机制进行动力学表征(校正非饱和成分和未搅动层之后)。2. 回肠中两种营养物质的实际Km均低于空肠,而Jmax则高于空肠,这表明至少对于己糖和氨基酸而言,回肠肠上皮细胞在功能上具备条件,且在解剖位置上也适宜充当小肠清道夫的角色。

相似文献

1
Comparison of jejunal and ileal absorptive functions for glucose and valine in vivo--a technique for estimating real Km and Jmax in the domestic fowl.家鸡体内空肠和回肠对葡萄糖和缬氨酸吸收功能的比较——一种估算家鸡真实米氏常数(Km)和最大转运速率(Jmax)的技术
Comp Biochem Physiol A Comp Physiol. 1983;74(4):961-6. doi: 10.1016/0300-9629(83)90377-8.
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Amino acid absorption in jejunum and ileum in vivo -- a kinetic comparison of function on surface area and regional bases.
Experientia. 1981 Mar 15;37(3):265-6. doi: 10.1007/BF01991646.
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The effects of fasting on the Real kinetic parameters for L-valine absorption measured in jejunum and ileum in vivo in fowls [proceedings].禁食对家禽空肠和回肠中L-缬氨酸吸收的实际动力学参数的影响[会议论文集]
J Physiol. 1979 Oct;295:20P-21P.
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The influence of molecular structure of neutral amino acids on their absorption kinetics in the jejunum and ileum of human intestine in vivo.中性氨基酸分子结构对其在人体空肠和回肠体内吸收动力学的影响。
Gastroenterology. 1969 May;56(5):903-13.
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Porceedings: The differential effects of starvation on the kinetics of electrogenic glucose adsorption in the jejunum and ileum of the domestic fowl (Gallus domesticus).会议论文:饥饿对家鸡(原鸡)空肠和回肠中电生性葡萄糖吸附动力学的不同影响。
J Physiol. 1976 May;257(1):31P-32P.
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引用本文的文献

1
Hexose transport across the apical and basolateral membrane of enterocytes from different regions of the chicken intestine.己糖在鸡肠道不同区域肠上皮细胞顶膜和基底外侧膜上的转运。
Pflugers Arch. 1994 Jan;426(1-2):83-8. doi: 10.1007/BF00374674.
2
Effect of feeding a high protein diet on amino acid uptake into rat intestinal brush border membrane vesicles.喂食高蛋白饮食对大鼠肠刷状缘膜囊泡氨基酸摄取的影响。
Pflugers Arch. 1984 Jan;400(1):34-9. doi: 10.1007/BF00670533.
3
Relationship between antipyrine absorption and blood flow rate in rat jejunum, ileum, and colon.
大鼠空肠、回肠和结肠中安替比林吸收与血流速率的关系。
Naunyn Schmiedebergs Arch Pharmacol. 1987 Jan;335(1):97-102. doi: 10.1007/BF00165043.
4
Diarrhoea of famine and malnutrition--investigations using a rat model. 2--Ileal hypersecretion induced by starvation.饥荒与营养不良性腹泻——大鼠模型研究。2——饥饿诱导的回肠分泌亢进
Gut. 1990 Feb;31(2):162-9. doi: 10.1136/gut.31.2.162.