Effects of acetylcholine and cholinolytics on the synaptic transmission in the ampullae of Lorenzini of the skate.
作者信息
Akoev G N, Andrianov G N, Sherman N O
出版信息
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1983;74(1):95-7. doi: 10.1016/0742-8413(83)90156-1.
PMID:6132777
Abstract
- The effects of ACh, D-tubocuraine and atropine on the electrical activity of the ampullae of Lorenzini of the skate were studied. 2. ACh (10(-5)M) caused an increase in frequency of afferent discharges in all receptors under study. 3. When excitability was abolished by high Mg2+ solution (50 mM) perfusion with 50 mM Mg2+ plus ACh did not induce firing in the afferent fibres. 4. Cholinergic antagonists (D-tub and atr) did not block the synaptic transmission. 5. The results suggest that ACh is unlikely to be the synaptic transmitter in the ampullae of Lorenzini.
摘要
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引用本文的文献
1
Neuropharmacological analysis of synaptic transmission in the Lorenzinian ampulla of the skate Raja clavata.
J Comp Physiol A. 1991 Jun;168(6):639-46. doi: 10.1007/BF00224354.
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