Schmitz-Valckenberg P
Klin Monbl Augenheilkd. 1983 Feb;182(2):150-2. doi: 10.1055/s-2008-1054734.
Elevated intraocular pressure during the first few days after routine intracapsular cataract extraction with and without alpha-chymotrypsin is a well-known symptom. A prospective, double-blind study was conducted to determine whether Metipranolol would prevent this increase in pressure. In 40 eyes which underwent routine, uncomplicated cataract extraction a drop of either Metipranolol 0,6% or placebo was administered before and during the first days after surgery. Prophylactic Metipranolol 0,6% can substantially reduce the incidence of severe early postoperative ocular hypertension.
在常规囊内白内障摘除术（无论是否使用α-糜蛋白酶）后的头几天内眼压升高是一种众所周知的症状。进行了一项前瞻性双盲研究，以确定美替洛尔是否能预防这种眼压升高。在40只接受常规、无并发症白内障摘除术的眼中，在手术前及术后头几天内滴入0.6%美替洛尔或安慰剂。预防性使用0.6%美替洛尔可大幅降低术后早期严重高眼压的发生率。
