Banciu T, Weidenfeld H, Marcoane E, Berinde L
Med Interne. 1983 Jan-Mar;21(1):23-9.
Gamma-glutamyltranspeptidase (GGTP) assay, clinical and morphologic investigations were performed in three groups of subjects: 1) 128 healthy subjects, exposed to high alcoholic risk; b) 97 chronic alcohol consumers, hospitalized; c) 87 patients with alcoholic liver disease (ALD) morphologically confirmed. The GGTP assay was positive in 80% of the drinkers; the values varying according to the amount and the duration of alcohol consumption. The correlation index between the GGTP values and the morphologic aspects was 0.51 for chronic drinkers with ALD. The positivity degree of this test and the anatomo-clinical aspects of liver injury were well correlated, maximum values corresponding with severe liver damage. Our results show the value of GGTP assay in the detection of chronic alcoholics and of ALD.
对三组受试者进行了γ-谷氨酰转肽酶（GGTP）检测、临床及形态学研究：1）128名有高酒精风险暴露的健康受试者；b）97名住院的慢性酒精饮用者；c）87名经形态学确诊的酒精性肝病（ALD）患者。80%的饮酒者GGTP检测呈阳性；其值根据饮酒量和饮酒持续时间而变化。对于患有ALD的慢性饮酒者，GGTP值与形态学方面的相关指数为0.51。该检测的阳性程度与肝损伤的解剖学临床方面密切相关，最大值对应严重肝损伤。我们的结果显示了GGTP检测在慢性酒精中毒者和ALD检测中的价值。
