Fischman L G
Schizophr Bull. 1983;9(1):73-94. doi: 10.1093/schbul/9.1.73.
Many observers have noted similarities between dreams, hallucinogenic drug states, and schizophrenia. In the present article, certain fundamental areas of convergence between the three states are described. Consideration is given to the hallucinogenic drug model of psychosis: the reasons for its initial attractiveness, and the reasons for its current disfavor. The concept of ego boundaries is defined, examined, and applied to the three states. In these states, the ego's capacity to average or synthesize various self-representations into a continuous, coherent self is compromised--leading to an impairment of the reality-oriented secondary process, and the emergence of the florid attributes of the primary process. This can account for many of the familiar characteristics of the three states. Current neurophysiological theories of dream and hallucinogenic drug states are presented, with emphasis upon serotonin neurotransmission. Serotonin appears to play a prominent role in the regulation of these states. The analogy contained in the present article suggests that serotonin may play a role in regulating schizophrenic states as well.
许多观察者已经注意到梦境、致幻药物状态和精神分裂症之间的相似之处。在本文中，描述了这三种状态之间某些基本的趋同领域。探讨了精神病的致幻药物模型：其最初具有吸引力的原因以及当前失宠的原因。对自我边界的概念进行了定义、审视并应用于这三种状态。在这些状态下，自我将各种自我表征平均化或综合为一个连续、连贯的自我的能力受到损害，导致以现实为导向的继发过程受损，以及原发过程的鲜明特征出现。这可以解释这三种状态的许多常见特征。本文介绍了当前关于梦境和致幻药物状态的神经生理学理论，重点是血清素神经传递。血清素似乎在这些状态的调节中起着重要作用。本文中的类比表明血清素可能在调节精神分裂症状态中也发挥作用。
