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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Levi H, Nielsen A, Ursin C

Comp Biochem Physiol A Comp Physiol. 1983;75(1):51-5. doi: 10.1016/0300-9629(83)90043-9.

Cell kinetic parameters in the epidermis of partially hypophysectomized, ACTH-treated toads whose moulting frequency was increased threefold were studied using labelled thymidine and the autoradiographic technique. 2. The labelling index, length of S-phase and cycle time of stratum germinativum cells changed slowly as a function of the number of ACTH injections, and so did the migration of cells from stratum germinativum to stratum corneum. 3. A cell production in stratum germinativum of normal toads in excess of cell loss, as demonstrated by Levi & Nielsen (1982) should make it possible to maintain a status quo over a limited period of time following ablation of pars distalis and ACTH treatment.

利用标记的胸腺嘧啶核苷和放射自显影技术，研究了部分垂体切除、经促肾上腺皮质激素（ACTH）处理且蜕皮频率增加三倍的蟾蜍表皮中的细胞动力学参数。2. 生发层细胞的标记指数、S期长度和细胞周期时间随ACTH注射次数的变化而缓慢改变，细胞从生发层向角质层的迁移情况也是如此。3. 如 Levi和 Nielsen（1982年）所证实的，正常蟾蜍生发层中的细胞生成超过细胞损失，这应使得在切除垂体远侧部并进行ACTH处理后的有限时间段内维持现状成为可能。

Levi H, Nielsen A, Ursin C

Comp Biochem Physiol A Comp Physiol. 1983;75(1):51-5. doi: 10.1016/0300-9629(83)90043-9.

Cell kinetic parameters in the epidermis of partially hypophysectomized, ACTH-treated toads whose moulting frequency was increased threefold were studied using labelled thymidine and the autoradiographic technique. 2. The labelling index, length of S-phase and cycle time of stratum germinativum cells changed slowly as a function of the number of ACTH injections, and so did the migration of cells from stratum germinativum to stratum corneum. 3. A cell production in stratum germinativum of normal toads in excess of cell loss, as demonstrated by Levi & Nielsen (1982) should make it possible to maintain a status quo over a limited period of time following ablation of pars distalis and ACTH treatment.

利用标记的胸腺嘧啶核苷和放射自显影技术，研究了部分垂体切除、经促肾上腺皮质激素（ACTH）处理且蜕皮频率增加三倍的蟾蜍表皮中的细胞动力学参数。2. 生发层细胞的标记指数、S期长度和细胞周期时间随ACTH注射次数的变化而缓慢改变，细胞从生发层向角质层的迁移情况也是如此。3. 如 Levi和 Nielsen（1982年）所证实的，正常蟾蜍生发层中的细胞生成超过细胞损失，这应使得在切除垂体远侧部并进行ACTH处理后的有限时间段内维持现状成为可能。