植物激素吲哚 - 3 - 乙酸及化学相关化合物对小鼠成纤维细胞3T3生长的影响。
The effect of the plant hormone indole-3-acetic acid and chemically related compounds on the growth of mouse fibroblast 3T3 cells.
作者信息
Abu Sinna G
出版信息
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1983;74(2):433-6. doi: 10.1016/0742-8413(83)90127-5.
PMID:6133692
Abstract
- The effect of the plant hormone indole-3-acetic acid (IAA) and the chemically related compounds: serotonin, tryptophan, I. pyruvic, I. butyric, I. propionic and tryptamine on the growth of 3T3 cells has been studied. 2. Each of these compounds increases the cell number in a variable degree. The increase is related to the presence of the serum in the medium. 3. The kinetic relation between IAA, foetal calf serum and cell growth was studied. 4. It may be that IAA and related compounds affect the cell growth through adenylate cyclase and cAMP-cGMP systems.
摘要
- 研究了植物激素吲哚 - 3 - 乙酸（IAA）以及化学相关化合物：血清素、色氨酸、吲哚丙酮酸、吲哚丁酸、吲哚丙酸和色胺对3T3细胞生长的影响。2. 这些化合物中的每一种都不同程度地增加了细胞数量。这种增加与培养基中血清的存在有关。3. 研究了IAA、胎牛血清与细胞生长之间的动力学关系。4. 可能IAA及相关化合物通过腺苷酸环化酶和cAMP - cGMP系统影响细胞生长。
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