Pavlakis A J, Siroky M B, Krane R J
J Urol. 1983 Jun;129(6):1182-4. doi: 10.1016/s0022-5347(17)52629-4.
We investigated 63 patients with detrusor areflexia by cystometrography, perineal floor electromyography and bethanechol chloride supersensitivity testing. Of the patients 48 had unequivocal evidence of neuropathy, while 15 were neurologically normal and served as controls. The bethanechol chloride supersensitivity test was positive in 98 per cent of the patients and none of the controls, whereas neuropathic changes by electromyography were found in 67 per cent of the patients and 7 per cent of the controls. These findings suggest that the bethanechol chloride supersensitivity test is more sensitive and more specific than perineal floor electromyography in corroborating bladder neuropathy.
我们通过膀胱测压法、会阴盆底肌电图和氯贝胆碱超敏试验对63例逼尿肌无反射患者进行了研究。在这些患者中，48例有明确的神经病变证据，而15例神经功能正常，作为对照。氯贝胆碱超敏试验在98%的患者中呈阳性，而对照组无一例阳性；而肌电图显示的神经病变改变在67%的患者中存在，在7%的对照组中存在。这些发现表明，在证实膀胱神经病变方面，氯贝胆碱超敏试验比会阴盆底肌电图更敏感、更具特异性。
