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[交感神经节炎患者的继发性间脑功能障碍及其病因治疗]

[Secondary diencephalic dysfunctions in patients with sympathoganglionitis and their pathogenetic treatment].

作者信息

Bulygin I A, Leonovich A L, Ginzburg S E, Kaliunov V N, Starostenko L I

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1983;83(4):515-22.

PMID:6134410
Abstract

Novel concepts of both the pathogenesis of secondary trunko-hypothalamic dysfunctions ("repercussive diencephaleses") associated with sympathoganglionites and their pathogenetic therapy are offered. They are based on new fundamental data concerning the physiology of vegetative ganglia, as well as on the findings of the clinical and electroencephalographic examinations, and the results of treatment of 67 patients with cervical sympathoganglionites. The suggested method of pathogenetic therapy consists of pharmacologically-induced blocking of the pathological afferent impulsation from the affected sympathetic ganglion; which is achieved by mild solutions of ganglioblockers administered into the ganglion; which is achieved by mild solutions of ganglioblockers administered into the ganglion by graded electrophoresis. Most of the patients showed a good therapeutic response. Data on the differential use of electrophoresis with either benzohexamethonium or gangleron, depending on the clinical manifestations of the disease, are presented.

摘要

本文提出了与交感神经节炎相关的继发性躯干 - 下丘脑功能障碍(“冲击性间脑病变”)的发病机制及其病因治疗的新概念。这些概念基于有关植物神经节生理学的新基础数据,以及临床和脑电图检查结果,还有67例颈交感神经节炎患者的治疗结果。所建议的病因治疗方法包括通过药理学方法阻断来自受影响交感神经节的病理性传入冲动;这是通过将神经节阻滞剂的稀溶液经分级电泳注入神经节来实现的。大多数患者显示出良好的治疗反应。文中还给出了根据疾病临床表现,分别使用苯六甲铵或甘罗溴铵进行电泳的差异数据。

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