Putative amino acid neurotransmitters and the nucleus dorsomedialis thalamus-prefrontal cortex pathway in the rat.

Endogenous levels of putative amino acid neurotransmitters (glycine, glutamic acid, aspartic acid, and GABA) in medial and sulcal prefrontal cortex of the rat were analyzed using gas liquid chromatography. No changes were found in the levels of these amino acids in medial and sulcal prefrontal cortex after lesion of the nucleus dorsomedialis of the thalamus suggesting, therefore, that the NDMT-prefrontal cortex pathway is not mediated by these amino acids.