大鼠体内假定的氨基酸神经递质与丘脑背内侧核-前额叶皮质通路
Putative amino acid neurotransmitters and the nucleus dorsomedialis thalamus-prefrontal cortex pathway in the rat.
作者信息
Peinado J M, Gomez-Capilla J A, Mora F, Osorio C
出版信息
Brain Res Bull. 1983 Apr;10(4):421-4. doi: 10.1016/0361-9230(83)90136-3.
PMID:6134571
Abstract
Endogenous levels of putative amino acid neurotransmitters (glycine, glutamic acid, aspartic acid, and GABA) in medial and sulcal prefrontal cortex of the rat were analyzed using gas liquid chromatography. No changes were found in the levels of these amino acids in medial and sulcal prefrontal cortex after lesion of the nucleus dorsomedialis of the thalamus suggesting, therefore, that the NDMT-prefrontal cortex pathway is not mediated by these amino acids.
摘要
使用气相色谱法分析了大鼠内侧和沟回前额叶皮质中假定的氨基酸神经递质（甘氨酸、谷氨酸、天冬氨酸和γ-氨基丁酸）的内源性水平。丘脑背内侧核损伤后，内侧和沟回前额叶皮质中这些氨基酸的水平未发现变化，因此表明，丘脑背内侧核-前额叶皮质通路不是由这些氨基酸介导的。
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