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首次吸毒体验所产生的强化作用能够预测日后的吸毒习惯及/或成瘾情况:以咖啡、香烟、酒精、巴比妥酸盐、短效和长效镇静剂、兴奋剂、大麻、致幻剂、海洛因、阿片类药物及可卡因为例的研究结果。

Reinforcements from the first drug experience can predict later drug habits and/or addiction: results with coffee, cigarettes, alcohol, barbiturates, minor and major tranquilizers, stimulants, marijuana, hallucinogens, heroin, opiates and cocaine.

作者信息

Haertzen C A, Kocher T R, Miyasato K

出版信息

Drug Alcohol Depend. 1983 Apr;11(2):147-65. doi: 10.1016/0376-8716(83)90076-5.

Abstract

The relationship between the reinforcing quality of the first drug experiences and eventual habits for a variety of drugs was studied in 42 male drug abusers who were predominantly opiate addicts. These subjects volunteered for drug studies carried out by the Addiction Research Center. The degree of reinforcement they derived from their first drug experience was related to their subsequent habit. This was true for alcohol, barbiturates, minor tranquilizers, cocaine, stimulants, marijuana, glue or solvents, hallucinogens, opiates other than heroin and heroin. Positive but non-significant correlations were found for coffee and major tranquilizers. The correlation for cigarettes was contrary to expectations. Of the components to the index of reinforcement, degree of liking of a drug on the first occasion was most related to the subsequent habit. The greatest initial reinforcement scores were found for heroin, cocaine and opiates other than heroin. drugs which were not well liked on the first occasion included major tranquilizers, cigarettes, coffee, and glue.

摘要

在42名主要为阿片类成瘾者的男性药物滥用者中,研究了初次用药体验的强化质量与多种药物最终成瘾习惯之间的关系。这些受试者自愿参与成瘾研究中心开展的药物研究。他们从初次用药体验中获得的强化程度与他们随后的成瘾习惯有关。酒精、巴比妥类药物、小剂量镇静剂、可卡因、兴奋剂、大麻、胶水或溶剂、致幻剂、除海洛因外的阿片类药物及海洛因均是如此。咖啡和大剂量镇静剂的相关性呈阳性但不显著。香烟的相关性与预期相反。在强化指数的各个组成部分中,初次对药物的喜爱程度与随后的成瘾习惯最为相关。海洛因、可卡因及除海洛因外的阿片类药物的初次强化得分最高。初次时不太受欢迎的药物包括大剂量镇静剂、香烟、咖啡和胶水。

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