Efinmov V S, Usov A I, Ol'skaia T S, Baliunis A I, Rozkin M Ia
Farmakol Toksikol. 1983 May-Jun;46(3):61-7.
Experiments in vitro and in vivo were made to study and compare anticoagulant activity and acute toxicity of a great number of sulfate polysaccharides isolated from red sea algae. Polysaccharides were identified, producing an appreciable anticoagulant effect similar to that of heparin. The heparin-like effect of polysaccharides from red sea algae depends on the structure of the carbohydrate chain and the degree of macromolecule sulfation.
进行了体外和体内实验，以研究和比较从红藻中分离出的大量硫酸多糖的抗凝活性和急性毒性。鉴定出了具有明显抗凝作用、类似于肝素的多糖。红藻多糖的类肝素作用取决于碳水化合物链的结构和大分子的硫酸化程度。
