大剂量静脉注射去铁胺的眼部毒性
Ocular toxicity of high-dose intravenous desferrioxamine.
作者信息
Davies S C, Marcus R E, Hungerford J L, Miller M H, Arden G B, Huehns E R
出版信息
Lancet. 1983 Jul 23;2(8343):181-4. doi: 10.1016/s0140-6736(83)90170-8.
PMID:6135026
Abstract
Desferrioxamine was given intravenously, at higher doses than previously reported, to counter the effects of transfusion-induced iron overload in four patients with beta thalassaemia major. In two of them retinal abnormalities developed, presenting with night blindness and field defects, which improved on withdrawal of the drug.
摘要
去铁胺通过静脉给药，剂量高于先前报道的剂量，用于对抗4例重型β地中海贫血患者因输血引起的铁过载的影响。其中2例出现视网膜异常，表现为夜盲和视野缺损，停药后症状改善。
Zotero 插件