一例合并胰岛母细胞瘤的多发性内分泌腺瘤病（1型），最终发展为胰腺外分泌癌。
A case of multiple endocrine adenomatosis (Type 1) with nesidioblastosis, terminating with an exocrine pancreatic carcinoma.
作者信息
Oliver M H, Drury P L, Van't Hoff W
出版信息
Clin Endocrinol (Oxf). 1983 May;18(5):495-403. doi: 10.1111/j.1365-2265.1983.tb02879.x.
Abstract
We describe a patient with multiple endocrine adenomatosis Type I, characterized by pituitary-dependent Cushing's Syndrome, marked hyperprolactinaemia, primary hyperparathyroidism and hyperinsulinism leading to hypoglycaemia. The patient subsequently developed an exocrine pancreatic carcinoma at the age of 32 years from which she died. An additional finding was the demonstration by immunocytochemistry of nesidioblastosis in the pancreas.
摘要
我们描述了一名患有I型多发性内分泌腺瘤病的患者，其特征为垂体依赖性库欣综合征、显著的高泌乳素血症、原发性甲状旁腺功能亢进和导致低血糖的高胰岛素血症。该患者随后在32岁时患上了外分泌性胰腺癌，并因此死亡。另一项发现是通过免疫细胞化学证实胰腺存在胰岛母细胞增殖症。
Zotero 插件