Brockman R P
Comp Biochem Physiol A Comp Physiol. 1983;75(2):201-3. doi: 10.1016/0300-9629(83)90070-1.
Glucose appearance and utilization before and during glucose infusions were examined in insulin treated alloxan-diabetic (ITA) and intact sheep. During hyperglycaemia in ITA sheep glucose appearance was reduced to 35% of the preinfusion values whereas in intact sheep it was 17% of preinfusion values. Hyperglycaemia per se appears to inhibit glucose appearance. The utilization of glucose was not proportional to glucose concentrations in ITA sheep, but was in intact sheep where insulin concentrations increased during hyperglycaemia.
在胰岛素治疗的四氧嘧啶糖尿病（ITA）绵羊和正常绵羊中，检测了葡萄糖输注前及输注期间葡萄糖的出现和利用情况。在ITA绵羊高血糖期间，葡萄糖出现率降至输注前值的35%，而在正常绵羊中为输注前值的17%。高血糖本身似乎会抑制葡萄糖出现。在ITA绵羊中，葡萄糖的利用与葡萄糖浓度不成比例，但在正常绵羊中，高血糖期间胰岛素浓度升高，葡萄糖利用与葡萄糖浓度成比例。
