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胰岛素和葡萄糖对绵羊(ovis aries)葡萄糖生成与利用的影响。

Effects of insulin and glucose on the production and utilization of glucose in sheep (Ovis aries).

作者信息

Brockman R P

出版信息

Comp Biochem Physiol A Comp Physiol. 1983;74(3):681-5. doi: 10.1016/0300-9629(83)90567-4.

DOI:10.1016/0300-9629(83)90567-4
PMID:6132712
Abstract
  1. The rates of appearance (RA) and metabolic clearance rates (MCR) of glucose were determined during the infusion of insulin plus glucose in sheep. 2. During euglycaemia 50% inhibition of RA of endogenous glucose occurred at insulin concentrations of 60 microU/ml in arterial plasma. 3. During euglycaemia the MCR of glucose doubled with an increment of about 100 microU/ml of insulin. 4. Hypoglycaemia was associated with a reduction in insulin's suppression of RA of endogenous glucose and hyperglycaemia significantly reduced the increase in MCR due to insulin.
摘要
  1. 在绵羊输注胰岛素加葡萄糖的过程中,测定了葡萄糖的出现率(RA)和代谢清除率(MCR)。2. 在血糖正常期间,动脉血浆中胰岛素浓度为60微单位/毫升时,内源性葡萄糖的RA受到50%的抑制。3. 在血糖正常期间,随着胰岛素增加约100微单位/毫升,葡萄糖的MCR增加了一倍。4. 低血糖与胰岛素对内源性葡萄糖RA抑制作用的降低有关,高血糖显著降低了胰岛素引起的MCR增加。

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Effects of insulin and glucose on the production and utilization of glucose in sheep (Ovis aries).胰岛素和葡萄糖对绵羊(ovis aries)葡萄糖生成与利用的影响。
Comp Biochem Physiol A Comp Physiol. 1983;74(3):681-5. doi: 10.1016/0300-9629(83)90567-4.
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