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[不同密度的林蛙动脉和静脉的功能特征以及血管运动神经支配的神经介质特性]

[Functional characteristics of Rana temporaria arteries and veins with different densities and neuromediator properties of vasomotor innervation].

作者信息

Leont'eva G R, Govyrin V A

出版信息

Zh Evol Biokhim Fiziol. 1983 May-Jun;19(3):237-44.

PMID:6136138
Abstract

Pharmacological studies have been made of frog's arteries and veins with different density and transmitter nature of their vasomotor innervation. It was found that the difference in vasomotor innervation of the blood vessels is related to the level of their maximal contractile response. The higher the adrenergic innervation, the higher the response to exogeneous catecholamines. The higher the cholinergic innervation, the higher the response to acetylcholine. Vasomotor innervation affects the sensitivity of the blood vessels, however catecholamine sensitivity is also observed in non-innervated vascular smooth muscle cells. alpha-Adrenoreceptors were found both in the innervated and non-innervated vessels, whereas beta-adrenoreceptors are present only in the innervated ones.

摘要

已对具有不同密度和血管运动神经支配递质性质的青蛙动脉和静脉进行了药理学研究。结果发现,血管的血管运动神经支配差异与其最大收缩反应水平有关。肾上腺素能神经支配越高,对外源性儿茶酚胺的反应就越高。胆碱能神经支配越高,对乙酰胆碱的反应就越高。血管运动神经支配会影响血管的敏感性,然而在无神经支配的血管平滑肌细胞中也观察到了儿茶酚胺敏感性。在有神经支配和无神经支配的血管中均发现了α-肾上腺素能受体,而β-肾上腺素能受体仅存在于有神经支配的血管中。

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