Govyrin V A
Zh Evol Biokhim Fiziol. 1977 Sep-Oct;13(5):614-20.
Histochemical, biochemical and electron microscopic studies of vasomotor innervation in onto- and phylogenesis of vertebrates reveal basic trends in evolution of the adrenegric apparatus of the blood vessels. In evolutionary row of animals, together with the development of hemodynamics, constant development of vasomotor innervation takes place, which reveals itself in the increase of the density of the adrenergic plexus and its mediator content. It was demonstrated that nerve-muscle relationships in vascular wall are not constant and depend on the degree of contraction of vascular muscles. Also inconstant are intercellular contacts of plain muscle fibers, their number and total surface being also dependent on the degree of vascular constriction. It is suggested that rearrangement of nerve-muscle and intermuscular relationships within the vascular wall during contraction-relaxation cycle automatically affects functional parameters of the blood vessel and provides for autoregulation purposes.
对脊椎动物个体发育和系统发育过程中血管运动神经支配的组织化学、生物化学及电子显微镜研究揭示了血管肾上腺素能装置的基本进化趋势。在动物进化序列中，随着血液动力学的发展，血管运动神经支配不断发展，表现为肾上腺素能神经丛密度及其介质含量增加。已证明血管壁中的神经 - 肌肉关系并非恒定不变，而是取决于血管肌肉的收缩程度。平滑肌纤维的细胞间接触也不稳定，其数量和总表面积同样取决于血管收缩程度。有人认为，在收缩 - 舒张周期中血管壁内神经 - 肌肉及肌间关系的重新排列会自动影响血管的功能参数，并实现自动调节目的。
