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[利用下丘脑促黑素检测垂体激素适应功能的演变]

[Evolution of the adaptive functions of hypophyseal hormones detected by using hypothalamic melanostatin].

作者信息

Mel'nik B E, Robu A I, Paladiĭ E S

出版信息

Nauchnye Doki Vyss Shkoly Biol Nauki. 1983(6):41-4.

PMID:6136302
Abstract

The content of two pituitary tropins (MSH and ACTH) has been determined in rats which were injected by the synthetic melanostatin to suppress MSH of the intermediate part of pituitary by radioimmune analysis. Besides, the function of the adrenal cortex according the content of corticosterone in various tissues was estimated. It has been revealed that the pituitary-adrenal complex activation is caused by the hypothalamic melanostatin suppression of the MSH secretion. All these testify the ACTH and MSH definite role in organisms adaptive reactions at different evolution steps.

摘要

通过放射免疫分析测定了注射合成褪黑素抑制垂体中间部促黑素(MSH)的大鼠体内两种垂体促激素(促黑素细胞激素和促肾上腺皮质激素)的含量。此外,根据各种组织中皮质酮的含量评估了肾上腺皮质的功能。结果表明,下丘脑褪黑素对促黑素分泌的抑制导致垂体 - 肾上腺复合体的激活。所有这些都证明了促肾上腺皮质激素和促黑素在生物不同进化阶段适应性反应中的明确作用。

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