Nerobkova L N, Voronina T A
Biull Eksp Biol Med. 1983 Aug;96(8):62-4.
It has been found in experiments on rats with chronically implanted electrodes that water-deprived rats as well as those under the conflict-punishment conditions demonstrated considerable activation of the hippocampal theta-rhythm. Phenazepam decreased the hippocampal theta-rhythm in water-deprived rats, whereas electric punishment did not produce any appreciable changes in the frequency spectrum on the electrogram. The data obtained suggest that an anticonflict (anxiolytic) effect of benzodiazepines is caused by the regulatory influence on the theta-rhythm in the hippocamp.
在对长期植入电极的大鼠进行的实验中发现，缺水的大鼠以及处于冲突-惩罚条件下的大鼠海马θ节律均有显著激活。芬那西泮可降低缺水大鼠的海马θ节律，而电惩罚并未使脑电图频谱产生任何明显变化。所获数据表明，苯二氮䓬类药物的抗冲突（抗焦虑）作用是由对海马θ节律的调节影响所致。
