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[Correlation between the pharmacokinetic indices and the pharmacological effects of fenazepam in an experiment].

作者信息

Zherdev V P, Voronina T A, Ekonomov A L, Martynova L A

出版信息

Farmakol Toksikol. 1985 Nov-Dec;48(6):67-70.

PMID:2867930
Abstract

A good agreement was established between the anxiolytic (tranquilizing) effect of phenazepam after administration to rats per os and the rate of its supply to the systemic blood flow. The magnitude of the myorelaxant effect of phenazepam in rats after its oral and intravenous administration correlated well with the drug concentration in blood only at the late periods of time.

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