da Cunha Bastos A, Salvatore C A, Faria R M
Int J Gynaecol Obstet. 1983 Apr;21(2):103-10. doi: 10.1016/0020-7292(83)90046-2.
In a study of the frozen section biopsy of 120 ovarian neoplasms, correct results were obtained in 94.16%, incorrect in 4.16%, and inconclusive in 1.66% of the 120 cases. The "incorrect" results were all "false-negative." No inverse "false-positive" results were recorded, and the "incorrect" results occurred in cases of encapsulated neoplasms of a macroscopically benign appearance with small areas of malignant changes detected only by paraffin block technique. The authors conclude that frozen section biopsy of ovarian neoplasm is plausible so long as a pathologist is available who can be provided with the proper equipment during the surgery and that the technique is more indicated in patients up to the age of 40 because of the necessity of conservative management in this age group.
在一项对120例卵巢肿瘤进行冰冻切片活检的研究中，120例病例的正确结果占94.16%，错误结果占4.16%，不确定结果占1.66%。“错误”结果均为“假阴性”。未记录到相反的“假阳性”结果，“错误”结果出现在肉眼外观为良性的包膜肿瘤病例中，这些病例只有通过石蜡块技术才能检测到小面积的恶性变化。作者得出结论，只要有病理学家在手术期间能够配备适当的设备，卵巢肿瘤的冰冻切片活检就是可行的，并且由于该年龄组需要进行保守治疗，该技术在40岁以下的患者中更适用。
