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三倍体的产前诊断。

Prenatal diagnosis of triploidy.

作者信息

Chatterjee M S, Tejani N A, Verma U L, Weiss R R

出版信息

Int J Gynaecol Obstet. 1983 Apr;21(2):155-7. doi: 10.1016/0020-7292(83)90054-1.

DOI:10.1016/0020-7292(83)90054-1
PMID:6136436
Abstract

Two cases of late midtrimester triploid gestation are presented. This unusual condition might be suspected in cases of first and second trimester bleeding when the uterus appears to be unusually large as estimated by the menstrual history. Early presence of gestational hypertension also points suggestively toward a triploid fetus. Ultrasound examination of the placenta typically shows multiple sonolucent areas. Confirmation of diagnosis is made by karyotyping cells obtained from amniotic fluid. The condition is incompatible with life and termination of pregnancy is indicated. It is considered prudent to follow HCG levels for evidence of persistent trophoblastic tissue.

摘要

本文报告了两例孕中期晚期三倍体妊娠病例。当根据月经史估计子宫异常增大时,在孕早期和孕中期出血的情况下可能会怀疑这种不寻常的情况。妊娠高血压的早期出现也提示可能存在三倍体胎儿。胎盘的超声检查通常显示多个无回声区。通过对羊水细胞进行核型分析来确诊。这种情况胎儿无法存活,应终止妊娠。监测血HCG水平以寻找持续性滋养层组织的证据被认为是谨慎的做法。

相似文献

1
Prenatal diagnosis of triploidy.三倍体的产前诊断。
Int J Gynaecol Obstet. 1983 Apr;21(2):155-7. doi: 10.1016/0020-7292(83)90054-1.
2
Placental changes in fetal triploidy syndrome.胎儿三倍体综合征中的胎盘变化。
J Ultrasound Med. 1986 Oct;5(10):545-50. doi: 10.7863/jum.1986.5.10.545.
3
A non-trophoblastic tumor co-existing with a triploid fetus.一个与三倍体胎儿并存的非滋养层肿瘤。
Early Pregnancy. 1995 Mar;1(1):67-71.
4
Triploid fetus: an important consideration in the evaluation of very high maternal serum alpha-fetoprotein.三倍体胎儿:评估孕妇血清甲胎蛋白水平极高时的一项重要考量因素。
Prenat Diagn. 1989 Jan;9(1):27-30. doi: 10.1002/pd.1970090105.
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The role of cordocentesis in assessment of mosaicism found in amniotic fluid cell culture.
Acta Obstet Gynecol Scand. 1994 Feb;73(2):119-22. doi: 10.3109/00016349409013413.
6
Sonographic features of the triploid fetus.三倍体胎儿的超声特征。
Am J Obstet Gynecol. 1987 Aug;157(2):285-7. doi: 10.1016/s0002-9378(87)80152-7.
7
Ascertainment of 68,XX double aneuploidy by midtrimester biochemical screening: a case report.孕中期生化筛查确诊68,XX双三体:一例报告
Am J Perinatol. 1998 Apr;15(4):229-32. doi: 10.1055/s-2007-993932.
8
[Triploidy as a cause of midtrimester gestosis(author's transl)].三倍体作为孕中期妊娠中毒症的一个病因(作者译)
Arch Gynakol. 1975;218(2):113-23. doi: 10.1007/BF01395911.
9
Detection of triploidy at 11-14 weeks' gestation: a cohort study of 198 000 pregnant women.11-14 孕周三胎的检测:一项 19.8 万例孕妇的队列研究。
Ultrasound Obstet Gynecol. 2013 Nov;42(5):530-5. doi: 10.1002/uog.12460. Epub 2013 Oct 9.
10
Diagnosis of a triploid fetus at genetic amniocentesis.在遗传羊膜腔穿刺术中诊断三倍体胎儿。
Obstet Gynecol. 1980 Jul;56(1):115-8.

引用本文的文献

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Maternal complications in molecularly confirmed diandric and digynic triploid pregnancies: single institution experience and literature review.分子确诊的双雄和双雌三倍体妊娠中的母体并发症:单机构经验及文献综述
Arch Gynecol Obstet. 2020 May;301(5):1139-1145. doi: 10.1007/s00404-020-05515-4. Epub 2020 Mar 26.
2
Triploidy after in vitro fertilization: cytogenetic analysis of human zygotes and embryos.
J Assist Reprod Genet. 1992 Feb;9(1):68-76. doi: 10.1007/BF01204118.