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在有和没有B细胞功能的胰岛素依赖型患者中,低血糖期间血浆生长抑素会增加。

Plasma somatostatin increases during hypoglycaemia in insulin-dependent patients with and without B-cell function.

作者信息

Madsbad S, Hilsted J, Krarup T, Tronier B, Sestoft L

出版信息

Clin Endocrinol (Oxf). 1983 Jul;19(1):47-51. doi: 10.1111/j.1365-2265.1983.tb00741.x.

DOI:10.1111/j.1365-2265.1983.tb00741.x
PMID:6137295
Abstract

Responses of somatostatin-like immunoreactivity (SLI) to hypoglycaemia were investigated in seven type 1 (insulin-dependent) patients with residual B-cell function, eight patients without B-cell function, and six healthy controls. A higher basal level of SLI was found in the group with B-cell function when compared with the group without B-cell function. The basal level in the normal subjects was in between the two diabetic groups. All the diabetics had a somatostatin response to hypoglycaemia which was independent of residual B-cell function and no different from that of normal subjects.

摘要

在7名具有残余B细胞功能的1型(胰岛素依赖型)患者、8名无B细胞功能的患者和6名健康对照者中,研究了生长抑素样免疫反应性(SLI)对低血糖的反应。与无B细胞功能的组相比,有B细胞功能的组中SLI的基础水平更高。正常受试者的基础水平介于两个糖尿病组之间。所有糖尿病患者对低血糖均有生长抑素反应,该反应与残余B细胞功能无关,且与正常受试者的反应无差异。

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Plasma somatostatin increases during hypoglycaemia in insulin-dependent patients with and without B-cell function.在有和没有B细胞功能的胰岛素依赖型患者中,低血糖期间血浆生长抑素会增加。
Clin Endocrinol (Oxf). 1983 Jul;19(1):47-51. doi: 10.1111/j.1365-2265.1983.tb00741.x.
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J Clin Invest. 1984 Aug;74(2):417-23. doi: 10.1172/JCI111437.

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