肺炎克雷伯菌中的一种新型抗甘露糖血凝素

A new mannose-resistant haemagglutinin in Klebsiella.

作者信息

Old D C, Adegbola R A

出版信息

J Appl Bacteriol. 1983 Aug;55(1):165-72. doi: 10.1111/j.1365-2672.1983.tb02661.x.

DOI:10.1111/j.1365-2672.1983.tb02661.x

Abstract

Strains of Klebsiella of the species (or 'patho-bio-sero-geogroups') Kl. atlantae, Kl. edwardsii and Kl. rhinoscleromatis produced neither haemagglutinins (HAs) nor fimbriae; strains of Kl. ozaenae were HA- but some produced type-6 fimbriae; and strains of Kl. pneumoniae (sensu stricto) and Kl. aerogenes that produced the mannose-sensitive HA (MS-HA) formed type-1 fimbriae. Most strains of Kl. aerogenes produced, in addition, one or both of the mannose-resistant HAs, MR/K-HA or MR/P-HA. The former, associated with type-3 fimbriae, was produced by 95%, and the latter by 57%, of the Kl. aerogenes strains. Some of the properties of the MR/P-HA, apparently a non-fimbrial HA not previously recognised in Klebsiella, are described.

摘要

亚特兰大克雷伯菌（或“致病生物血清地理群”）、爱德华氏克雷伯菌和鼻硬结克雷伯菌菌株既不产生血凝素（HA）也不产生菌毛；臭鼻克雷伯菌菌株不产生HA，但有些产生6型菌毛；肺炎克雷伯菌（狭义）和产气克雷伯菌菌株产生甘露糖敏感HA（MS-HA）并形成1型菌毛。此外，大多数产气克雷伯菌菌株还产生一种或两种甘露糖抗性HA，即MR/K-HA或MR/P-HA。前者与3型菌毛相关，95%的产气克雷伯菌菌株产生该种HA，后者产生率为57%。本文描述了MR/P-HA的一些特性，它显然是一种以前在克雷伯菌中未被识别的非菌毛HA。