Weaver A D
Vet Rec. 1983 Jul 30;113(5):105-7. doi: 10.1136/vr.113.5.105.
Sixty-seven cases of canine sertoli cell tumour are reviewed. The mean age at diagnosis was 9.5 years (sd +/- 2.1, range 3 to 17). The most commonly affected breeds were boxer, cairn terrier, labrador retriever, border collie, German shepherd and rough collie. The left side was affected in 28 dogs (42 per cent), the right in 35 (52.5 per cent) and both sides in four (6 per cent). Twenty testicles were abdominal (left, seven; right, 13), seven were inguinal (left, four; right, three) and 44 were scrotal (left, 21; right, 23). Hormonal signs were evident in 38 (57 per cent) animals (feminisation with alopecia in 21, symmetrical alopecia alone in 17). Other types of testicular tumours were found in 12 dogs (18 per cent) of this series. Of 42 dogs which were castrated and discharged, 38 were available for follow-up study and survived for between one week and five years. Two of the 15 dogs which were subject to post mortem examination had metastases. Two others which died after failure of remission, or a recurrence of the hormonal changes probably also had metastases. Two of the 25 dogs which were presented initially for other reasons, but had sertoli cell tumours, were found to have metastases post mortem. The boxer, cairn terrier, border collie, Shetland collie and pekingese had a higher risk of sertoli cell tumour than other breeds.
回顾了67例犬支持细胞瘤病例。诊断时的平均年龄为9.5岁（标准差±2.1，范围3至17岁）。最常受影响的品种是拳师犬、凯恩梗、拉布拉多寻回犬、边境牧羊犬、德国牧羊犬和粗毛柯利犬。28只犬（42%）左侧患病，35只犬（52.5%）右侧患病，4只犬（6%）双侧患病。20个睾丸位于腹腔内（左侧7个；右侧13个），7个位于腹股沟区（左侧4个；右侧3个），44个位于阴囊内（左侧21个；右侧23个）。38只（57%）动物出现激素相关体征（21只出现伴有脱毛的雌性化，17只仅出现对称性脱毛）。本系列中12只犬（18%）发现了其他类型的睾丸肿瘤。42只接受去势并出院的犬中，38只可进行随访研究，存活时间为1周至5年。15只接受尸检的犬中有2只发生了转移。另外2只在缓解失败或激素变化复发后死亡的犬可能也发生了转移。最初因其他原因就诊但患有支持细胞瘤的25只犬中，有2只在尸检时发现有转移。拳师犬、凯恩梗、边境牧羊犬、设得兰牧羊犬和北京犬患支持细胞瘤的风险高于其他品种。
