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13-顺式维甲酸对大鼠下颌下唾液腺脂肪酸组成及膜相关酶的影响。

Effect of 13-cis retinoic acid on fatty acid composition and membrane-associated enzymes in rat submandibular salivary glands.

作者信息

Alam S Q, Alam B S

出版信息

Arch Oral Biol. 1983;28(6):507-11. doi: 10.1016/0003-9969(83)90182-6.

DOI:10.1016/0003-9969(83)90182-6
PMID:6138021
Abstract

Weanling rats were fed for 4 weeks semipurified diets containing 0, 100 or 300 mg 13-cis retinoic acid per kg diet. The activities of (Na+ + K+)-ATPase, Mg2+-ATPase and gamma-glutamyltranspeptide were measured in submandibular salivary gland (SMSG) homogenates. The activity of (Na+ + K+)-ATPase in the SMSG was reduced in rats fed 13-cis retinoic acid. There was no effect on the activities of the other two enzymes. Fatty acid composition of total lipids in SMSG suggest that decrease in (Na+ + K+)-ATPase activity may be associated with changes in fatty acid composition of total lipids.

摘要

将断乳大鼠用每千克饲料含0、100或300毫克13 - 顺式视黄酸的半纯化饲料喂养4周。测定下颌下唾液腺(SMSG)匀浆中(Na⁺ + K⁺)-ATP酶、Mg²⁺-ATP酶和γ-谷氨酰转肽酶的活性。喂食13 - 顺式视黄酸的大鼠下颌下唾液腺中(Na⁺ + K⁺)-ATP酶的活性降低。对其他两种酶的活性没有影响。下颌下唾液腺中总脂质的脂肪酸组成表明,(Na⁺ + K⁺)-ATP酶活性的降低可能与总脂质脂肪酸组成的变化有关。

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